PMID: 11926750Apr 3, 2002Paper

Role of cytomegalovirus in cardiac allograft vasculopathy

Transplant Infectious Disease : an Official Journal of the Transplantation Society
D Weill

Abstract

Cardiac allograft vasculopathy is the most common cause of death and retransplantation following heart transplantation, and about 10% of patients per year have evidence of accelerated vascular disease; 50% at 5 years. Cytomegalovirus (CMV) infection has been associated with accelerated cardiac vasculopathy and decreased 5-year survival. Prophylactic therapy using ganciclovir has reduced the incidence of CMV disease, but not in the group at highest risk, namely the seronegative recipient of an allograft from a seropositive donor (D+/R-). Combination prophylaxis consisting of CMV hyperimmune globulin (CMV-IGIV) plus ganciclovir is associated with decreased intimal thickening, reduced coronary artery disease and obliterative bronchiolitis, and improved survival.

References

Apr 30, 1992·The New England Journal of Medicine·T C MeriganR M Ratkovec
Jun 23, 1989·JAMA : the Journal of the American Medical Association·M T GrattanN E Shumway
Jan 1, 1993·Transplant International : Official Journal of the European Society for Organ Transplantation·P K KoskinenI T Lautenschlager
Oct 10, 1997·Circulation·M Weis, W von Scheidt
Nov 5, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·T M WoleverM H Tan

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Citations

Aug 17, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Ingrid M SeipeltSusan E Crawford
Apr 3, 2002·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R H Rubin
Sep 15, 2005·The Journal of Cardiovascular Nursing·Frances M Hoffman
Feb 1, 2005·Journal of Virology·Afsar Rahbar, Cecilia Söderberg-Nauclér
Apr 9, 2011·Herpesviridae·Stefania Varani, Maria Paola Landini
Nov 19, 2011·Primary Care·Christopher P Raab
Jan 23, 2008·Enfermedades infecciosas y microbiología clínica·María José Pérez-SolaJulián Torre-Cisneros
Oct 9, 2007·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Supha Kijpittayarit-ArthursRaymund R Razonable
May 25, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Jan-Luuk HillebrandsJan Rozing
Nov 22, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Juho T LehtoPetri K Koskinen
Sep 28, 2012·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J KobashigawaL Potena
Sep 12, 2009·Transplant Infectious Disease : an Official Journal of the Transplantation Society·M ViganòUNKNOWN RAD A2411 Study Investigators
Sep 29, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·William T MahleUNKNOWN Pediatric Heart Transplant Study Group
Feb 24, 2016·Transplantation·Paolo GrossiLuciano Potena
Jun 3, 2021·Pathogens·Cassandra M Bonavita, Rhonda D Cardin

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