Role of Doppler Diastolic Parameters in Differentiating Physiological Left Ventricular Hypertrophy from Hypertrophic Cardiomyopathy

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Gherardo FinocchiaroSanjay Sharma

Abstract

The association between athletic participation and alteration in diastolic function is not well established. The aims of this study were to determine the spectrum of Doppler parameters of left ventricular (LV) diastolic function in a large cohort of healthy athletes and to quantify the overlap between physiologic LV hypertrophy and hypertrophic cardiomyopathy (HCM). A retrospective analysis of indices of LV diastolic function was performed in 1,510 healthy athletes (mean age, 22 ± 5 years; range, 13-33 years; 72% men). The results were compared with those from 58 young patients with HCM. Septal E' < 7 cm/sec and lateral E' < 10 cm/sec were found in five (0.3%) and eight (0.5%) athletes, respectively. Septal E' was >14.6 cm/sec in 170 (11%) and lateral E' was >19.9 cm/sec in 430 (28%) athletes. Athletes aged >25 years showed lower E' velocities compared with younger athletes (mean septal E', 11.8 ± 6.1 vs 12.9 ± 5.9 cm/sec [P < .001]; mean lateral E', 17.1 ± 3.6 vs 19.3 ± 4.1 cm/sec [P < .001]). Athletes with high indexed LV end-diastolic diameters (>32 mm/m2) exhibited lower septal E' compared with athletes with normal indexed LV end-diastolic diameters (mean septal E', 11.9 ± 6 vs 12.7 ± 6 cm/sec; P = .002). Septal E' < 10 cm/...Continue Reading

Citations

Oct 28, 2018·Current Treatment Options in Cardiovascular Medicine·Daniel X Augustine, Liz Howard
Mar 19, 2020·Scandinavian Journal of Medicine & Science in Sports·Benjamin BrownDavid Oxborough
May 16, 2020·Journal of Cardiovascular Translational Research·Marc AbulíMarta Sitges
Jul 17, 2018·The International Journal of Cardiovascular Imaging·Hélder DoresJosé Ferreira Santos
Aug 28, 2018·Current Treatment Options in Cardiovascular Medicine·Lynsey ForsytheDavid Oxborough
Dec 22, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Chihiro SaitoNobuhisa Hagiwara

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