Role of dynamic MRI in differentiating benign from malignant follicular thyroid nodule

Auris, Nasus, Larynx
Nikhil GuptaArun Kakar

Abstract

Thyroid nodular swellings are very common, consisting of both benign and malignant ones. Fine needle aspiration cytology is an excellent diagnostic modality for papillary cancers, medullary cancers, colloid goiter and lymphoma but fails in differentiating follicular adenomas from carcinomas. The purpose of this study was to evaluate role of Dynamic MRI with signal intensity time curve evaluation in differentiating benign from malignant follicular nodules. This study was carried out in Department of Surgery in collaboration with department of Radiodiagnosis, Maulana Azad Medical College, Delhi. 28 patients with solitary thyroid nodule (STN) having follicular etiologies were included in the study. Dynamic MRI with signal intensity time curve analysis was carried out in all the cases and findings were compared with the final diagnosis based on histopathological examination of surgical specimen. In the present study, rapid enhancement was seen in 87.5% of malignant cases and washout pattern was seen in 87.5% of malignant STN (p=0.019). Only 20% of the benign lesions showed washout pattern (p=0.0034). Benign cases demonstrated gradual enhancement in 85% cases as compared to 12.5% in malignant STN (p=0.0098). This study suggests that...Continue Reading

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Citations

Sep 30, 2015·Journal of Computer Assisted Tomography·Eliel Ben-DavidM Reza Taheri
Sep 22, 2015·Journal of Magnetic Resonance Imaging : JMRI·Ruoyang ShiYan Zhou
May 23, 2012·European Journal of Radiology·Ying YuanXiao-Feng Tao
Nov 20, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Muhammed Sedat SakatMecit Kantarcı

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