Role of dynamic perfusion magnetic resonance imaging in patients with local advanced rectal cancer.

World Journal of Gastroenterology : WJG
Davide IppolitoSandro Sironi

Abstract

The management of rectal cancer patients is mainly based on the use of the magnetic resonance imaging (MRI) technique as a diagnostic tool for both staging and restaging. After treatment, to date, the evaluation of complete response is based on the histopathology assessment by using different tumor regression grade (TRG) features (e.g., Dworak or Mandard classifications). While from the radiological point of view, the main attention for the prediction of a complete response after chemotherapy treatment focuses on MRI and the potential role of diffusion-weighted images and perfusion imaging represented by dynamic-contrast enhanced MRI. The main aim is to find a reliable tool to predict tumor response in comparison to histopathologic findings. To investigate the value of dynamic contrast-enhanced perfusion-MRI parameters in the evaluation of the healthy rectal wall and tumor response to chemo-radiation therapy in patients with local advanced rectal cancer with histopathologic correlation. Twenty-eight patients with biopsy-proven rectal adenocarcinoma who underwent a dynamic contrast-enhanced MR study performed on a 1.5T MRI system (Achieva, Philips), before (MR1) and after chemoradiation therapy (MR2), were enrolled in this study...Continue Reading

References

Mar 3, 2007·The Lancet Oncology·Vicky GohShahnawaz Rasheed
Apr 1, 2010·World Journal of Gastroenterology : WJG·Choon Hua ThngDow Mu Koh
Apr 7, 2010·European Journal of Radiology·Steven Sourbron
Aug 27, 2013·AJR. American Journal of Roentgenology·Andrew B RosenkrantzFang-Ming Deng
Oct 11, 2013·Frontiers in Oncology·Svenja Thies, Rupert Langer
Oct 16, 2013·Journal of Magnetic Resonance Imaging : JMRI·André LollertKatja Oberholzer
Sep 28, 2014·International Journal of Radiation Oncology, Biology, Physics·Alexander Friedrich DeVriesDietmar Öfner
Nov 14, 2014·Current Opinion in Gastroenterology·Perry J Pickhardt
Dec 17, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Milou H MartensRegina G H Beets-Tan
Oct 11, 2017·European Journal of Radiology·Rebecca A P DijkhoffMonique Maas
Jun 23, 2018·World Journal of Gastroenterology : WJG·Davide IppolitoRiccardo Faletti
Jul 1, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R Glynne-JonesUNKNOWN ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org

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Citations

Apr 28, 2021·Magnetic Resonance Imaging·Levebvre JulieBalvay Daniel

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Methods Mentioned

BETA
imaging technique

Software Mentioned

R
SPSS
Intellispace

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