PMID: 9438853Feb 7, 1998Paper

Role of dynamin in the formation of transport vesicles from the trans-Golgi network

Science
S M JonesM A McNiven

Abstract

Dynamin guanosine triphosphatases support the scission of clathrin-coated vesicles from the plasmalemma during endocytosis. By fluorescence microscopy of cultured rat hepatocytes, a green fluorescent protein-dynamin II fusion protein localized with clathrin-coated vesicles at the Golgi complex. A cell-free assay was utilized to demonstrate the role of dynamin in vesicle formation at the trans-Golgi. Addition of peptide-specific anti-dynamin antibodies to the assay mixture inhibited both constitutive exocytic and clathrin-coated vesicle formation. Immunodepletion of dynamin proteins also inhibited vesicle formation, and budding efficiency was restored upon readdition of purified dynamin. These data suggest that dynamin participates in the formation of distinct transport vesicles from the trans-Golgi network.

References

Apr 1, 1990·Developmental Biology·C A Poodry
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J SalameroK E Howell
Jan 24, 1973·Molecular & General Genetics : MGG·T A GrigliattiD T Suzuki
Mar 9, 1995·Nature·R B Kelly
Jan 18, 1994·Proceedings of the National Academy of Sciences of the United States of America·T A CookM A McNiven
Aug 1, 1993·The Journal of Cell Biology·J S HerskovitsR B Vallee
May 1, 1996·The Journal of Cell Biology·J R Henley, M A McNiven
Jun 14, 1996·Biochemical and Biophysical Research Communications·O MaierP Westermann
Sep 1, 1996·Journal of Neurochemistry·T CookR Urrutia
Jan 21, 1997·Proceedings of the National Academy of Sciences of the United States of America·R UrrutiaM A McNiven
Jul 1, 1997·Trends in Cell Biology·B Kelly

❮ Previous
Next ❯

Citations

Dec 18, 2001·Journal of Cellular Biochemistry·S Y YoonM Y Han
Feb 4, 2010·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Anne-Cécile DurieuxMarc Bitoun
Apr 24, 2013·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Laura BriñasMarc Bitoun
Oct 30, 2012·Cell Reports·Comert KuralTom Kirchhausen
Apr 9, 2005·Trends in Plant Science·Desh Pal S Verma, Zonglie Hong
Jul 2, 1999·Biophysical Journal·M M Kozlov
Dec 14, 2002·Journal of Hepatology·Ahmad S AbdulkarimMark A McNiven
Jul 10, 2003·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Andrew M ArnoldNorman L Eberhardt
Jan 9, 2003·Current Opinion in Cell Biology·James D Orth, Mark A McNiven
Oct 18, 2002·Current Opinion in Cell Biology·Maria De MatteisDaniela Corda
Aug 28, 1998·Current Opinion in Cell Biology·S L SchmidP De Camilli
May 14, 1999·Current Opinion in Structural Biology·J E Hinshaw
Apr 14, 1999·Trends in Cell Biology·A M van der Bliek
May 14, 1999·Trends in Cell Biology·M G Roth
Mar 1, 2000·Trends in Biochemical Sciences·M A McNivenY Yoon
Feb 3, 2000·Nature Cell Biology·G KreitzerE Rodriguez-Boulan
May 10, 2005·Nature Cell Biology·Matteo BonazziAlberto Luini
Aug 23, 2005·Nature Cell Biology·Esteban Veiga, Pascale Cossart
Oct 18, 2005·Nature Genetics·Marc BitounPascale Guicheney
Jan 12, 2012·Nature Reviews. Molecular Cell Biology·Shawn M Ferguson, Pietro De Camilli
Mar 23, 2002·The Pharmacogenomics Journal·P Schu
Mar 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shaun G WellerMark A McNiven
Dec 3, 2011·The Journal of Biological Chemistry·Ameet A ChimoteLaura Conforti
Sep 15, 2012·The Journal of Biological Chemistry·Andrew T ReidBrett Nixon
Oct 23, 2013·The Journal of Cell Biology·Ryan J SchulzeMark A McNiven
Dec 22, 1999·The Journal of Experimental Medicine·E S GoldA Aderem
Jan 26, 2002·Molecular Biology of the Cell·Ellen M van Dam, Willem Stoorvogel
Sep 13, 2001·Molecular Biology of the Cell·Y YoonM A McNiven
Sep 3, 1998·Molecular Biology of the Cell·H CaoM A McNiven
Jul 1, 2005·Molecular Biology of the Cell·Katy Janvier, Juan S Bonifacino
May 27, 2008·The Plant Cell·Catherine A KonopkaSebastian Y Bednarek
Oct 21, 2010·The Plant Cell·Steven K BackuesSebastian Y Bednarek
Dec 23, 2004·Science's STKE : Signal Transduction Knowledge Environment·Thierry Galli, Volker Haucke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved