PMID: 6414280Sep 22, 1983Paper

Role of electrophysiologic techniques in the selection of antiarrhythmic drug regimens for ventricular arrhythmias

The American Journal of Cardiology
J N RuskinH Garan

Abstract

Programmed electrical stimulation of the heart provides a useful new technique for guiding the selection of antiarrhythmic drug regimens in selected patients with ventricular tachycardia (VT) or ventricular fibrillation. The technique of programmed electrical stimulation has been applied successfully in patients with recurrent sustained VT, out-of-hospital ventricular fibrillation and unexplained syncope in the presence of structural heart disease. The complete suppression of VT induced by programmed electrical stimulation by a drug regimen is highly predictive of freedom from both recurrent VT and sudden death. In addition, this technique may hold promise as a means of assessing the arrhythmogenic effects of antiarrhythmic drugs in selected patients.

References

Sep 4, 1976·Lancet·J M ClarkeG R Venning
Mar 1, 1979·The American Journal of Cardiology·M E Josephson, L N Horowitz
Oct 5, 1978·The New England Journal of Medicine·H L GreeneA H Schaeffer
Aug 1, 1976·The American Journal of Cardiology·H L Kennedy, S J Underhill
Mar 1, 1980·Current Problems in Cardiology·B LownT B Graboys
Jun 1, 1982·British Heart Journal·S W RabkinR B Tate
Jul 1, 1982·Pacing and Clinical Electrophysiology : PACE·T R Engel
Sep 1, 1982·The American Journal of Cardiology·T B GraboysR DeSilva
Apr 1, 1982·American Heart Journal·D P ZipesJ J Heger
Feb 1, 1983·Journal of the American College of Cardiology·C D SwerdlowJ W Mason
Jun 16, 1983·The New England Journal of Medicine·C D SwerdlowJ W Mason
Sep 1, 1980·The American Journal of Cardiology·A M GreenspanM E Josephson
Feb 26, 1982·JAMA : the Journal of the American Medical Association·M Akhtar
Apr 23, 1981·The New England Journal of Medicine·J A KastorM E Josephson
Feb 5, 1982·JAMA : the Journal of the American Medical Association·M Akhtar
Apr 1, 1982·American Heart Journal·L N HorowitzM E Josephson
Sep 1, 1982·The American Journal of Cardiology·F D LivelliJ I Gliklich
Oct 1, 1982·Annals of Internal Medicine·J P DimarcoJ N Ruskin
Nov 1, 1981·Annals of Internal Medicine·J P DiMarcoJ N Ruskin
Apr 1, 1980·The American Journal of Cardiology·C J VandepolM E Josephson
Jul 1, 1980·American Heart Journal·A FarshidiM E Josephson
Dec 1, 1980·The American Journal of Cardiology·T R EngelJ C Luck
Dec 1, 1980·The American Journal of Cardiology·M E JosephsonA M Greenspan

❮ Previous
Next ❯

Citations

Jan 1, 1985·Molecular Aspects of Medicine·J H BottingM J Walker
Oct 19, 1988·The American Journal of Cardiology·D L KucharJ N Ruskin
Jan 1, 1988·Circulation·J M SmithR J Cohen
Jul 1, 1988·Pacing and Clinical Electrophysiology : PACE·R N FogorosJ J Elson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.