Role of endogenous pain modulation in chronic pain mechanisms and treatment

Pain
David Yarnitsky

Abstract

Development and application of psychophysical test paradigms to assess endogenous pain modulation in healthy controls and in patients yielded large body of data over the last 2 decades. These tests can assist in predicting pain acquisition, in characterizing pain syndromes and related dysfunctions of pain modulation, and in predicting response to treatment. This chapter reviews the development of thought on pain modulation in the clinical setup, focusing on conditioned pain modulation, and update on accumulated data regarding the mechanism, protocols of administration, and applications in the clinic.

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Citations

Feb 5, 2016·The Journal of Pain : Official Journal of the American Pain Society·Andrew FloodStuart Cathcart
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Jan 31, 2019·Scandinavian Journal of Pain·Jürg SchliessbachMichele Curatolo

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