Role of estrogen and progesterone in the regulation of uterine peristalsis: results from perfused non-pregnant swine uteri

Human Reproduction
A MuellerR Dittrich

Abstract

Adequate uterine contractility and peristalsis are involved in the transport of semen and gametes and in successful embryo implantation. Estrogen and progesterone fluctuate characteristically during the menstrual cycle. It has been suggested that both hormones influence uterine peristalsis in characteristic ways. An extracorporeal perfusion model of the swine uterus was used that keeps the uterus in a functional condition and is suitable for the study of physiological questions. The effects of estrogen and progesterone on oxytocin-induced uterine peristalsis were assessed using an intrauterine double-chip microcatheter. Estrogen perfusion was associated with an increase in intrauterine pressure (IUP) in a dose-dependent manner. There was a significant difference between the IUP increase measured in the isthmus uteri and that in the corpus uteri, resulting in a cervico-fundal pressure gradient. Estrogen perfusion resulted in a significantly higher rate of peristaltic waves starting in the isthmus uteri and directed towards the corpus uteri. Progesterone was able to antagonize the estrogen effect in general. This study demonstrates that estrogen and progesterone have differential effects in the regulation of uterine peristalsis. ...Continue Reading

References

Jan 1, 1992·Neuroscience and Biobehavioral Reviews·C S Carter
Oct 1, 1990·The Journal of Clinical Endocrinology and Metabolism·M R MurphyS L Lightman
Jun 1, 1988·Fertility and Sterility·C BullettiC Flamigni
Jan 1, 1987·The Journal of Clinical Endocrinology and Metabolism·M S CarmichaelJ M Davidson
Mar 1, 1986·American Journal of Obstetrics and Gynecology·C BullettiE Gurpide
Jan 22, 1983·British Medical Journal·A S McNeillyP W Howie
Jan 1, 1984·Fertility and Sterility·J C Birnholz
Jun 1, 1994·Human Reproduction·M Fukuda, K Fukuda
Aug 6, 1998·The Journal of Endocrinology·J A Russell, G Leng
Aug 6, 2000·Human Reproduction·R FanchinR Frydman
Mar 29, 2001·Physiological Reviews·G Gimpl, F Fahrenholz
Jun 29, 2001·Experimental Physiology·S ThorntonD Slater
Dec 1, 2001·Human Reproduction·C BullettiE Cincinelli
Jun 12, 2002·Fertility and Sterility·Carlo BullettiCarlo Flamigni
Jul 12, 2003·Brain Research. Developmental Brain Research·Mario CabaRae Silver
Sep 5, 2003·Biology of Reproduction·Kathrin A Dunlap, Fredrick Stormshak
Oct 1, 2003·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·R DittrichM W Beckmann
Nov 8, 2003·Archives of Gynecology and Obstetrics·Oliver N RichterEva Wardelmann
Jan 30, 2004·American Journal of Obstetrics and Gynecology·Nicola A WoodcockSteven Thornton
Apr 6, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S KisslerE Siebzehnruebl
Feb 26, 2005·Annals of the New York Academy of Sciences·Gerhard LeyendeckerLudwig Wildt
May 5, 2005·Current Opinion in Obstetrics & Gynecology·Carlo Bulletti, Dominique de Ziegler
Jul 20, 2005·Journal of Magnetic Resonance Imaging : JMRI·Aki KidoShingo Fujii
Aug 30, 2005·Current Topics in Developmental Biology·Thomas E SpencerKaren D Carpenter
Sep 20, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·S KisslerM Kaufmann

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Citations

Aug 26, 2011·American Journal of Physiology. Cell Physiology·Andrei A TicaEugen Brailoiu
Dec 18, 2012·Reproductive Biology and Endocrinology : RB&E·Klaudija GeislerRalf Dittrich
Feb 9, 2007·The Tohoku Journal of Experimental Medicine·Tuncay NasYusuf Sarioğlu
May 8, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Andrea CiavattiniAndrea Luigi Tranquilli
Nov 11, 2011·Journal of Minimally Invasive Gynecology·Osamu YoshinoToshihiko Hayashi
Nov 17, 2009·Reproductive Biomedicine Online·Luca Dal Prato, Andrea Borini
Nov 3, 2009·Theriogenology·D K BergP L Pfeffer
Feb 20, 2007·Annals of the New York Academy of Sciences·Panagiotis BeretsosAris Antsaklis
Jun 21, 2014·Reproduction in Domestic Animals = Zuchthygiene·A GramM P Kowalewski
Jun 6, 2018·BMC Veterinary Research·Malgorzata DominoZdzislaw Gajewski
Jul 3, 2019·Interface Focus·Ying ZhangDavid Elad
Jul 17, 2021·PloS One·Aleksandra ZygmuntowiczJerzy Jan Jaroszewski
Sep 4, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Nattapong BuddhabunyakanLingling Salang

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