Role of foods in irregular aggravation of skin lesions in children with atopic dermatitis

The Journal of Dermatology
T UenishiM Uehara

Abstract

Atopic dermatitis is a common inflammatory skin disease that especially affects children and adolescents. Many environmental factors have been recognized as relevant in aggravating skin lesions of the disease. However, it remains to be determined whether foods play a role in worsening of skin lesions in children with atopic dermatitis. In the present study, we investigated whether foods play a role in irregular aggravation of skin lesions in children with the disease. The study population consisted of 69 patients aged 3-15 years with atopic dermatitis. They were hospitalized and open challenge tests were performed with suspected foods. Photographs of representative skin lesion sites were taken at baseline and before and after the challenge. We determined challenge-positive foods by evaluating the comparable before/after challenge photographs. One to three (average, 1.9) challenge-positive foods were confirmed in 52 (75%) of the 69 patients examined. Predominant offending foods were chocolate, cheese and yogurt. Specific immunoglobulin E values to offending foods were mostly negative. We asked patients to exclude challenge-positive foods from their diets. They were then discharged and followed up for 3 months at our outpatient c...Continue Reading

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Citations

Sep 30, 2014·Journal of the American Academy of Dermatology·Robert SidburyLawrence F Eichenfield
Aug 25, 2015·Current Allergy and Asthma Reports·Jeffrey F ScottSusan T Nedorost
Sep 3, 2010·Dermato-endocrinology·Nathalie Piccardi, Patricia Manissier
May 30, 2013·Annals of Dermatology·Hye One KimCheol Heon Lee
Sep 9, 2017·Pediatric Dermatology·Neil R LimPeter A Lio
Aug 26, 2021·International Journal of Dermatology·Supaporn SuwanchoteDirekrit Chiewchengchol
Aug 20, 2009·Current Opinion in Allergy and Clinical Immunology

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Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

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