PMID: 11338125May 8, 2001Paper

Role of hepatitis E and other hepatotropic virus in aetiology of sporadic acute viral hepatitis: a hospital based study from urban Delhi

European Journal of Epidemiology
K DasP Kar

Abstract

Major hepatotropic virus continues to be an important cause of acute viral hepatitis (AVH) in developing countries like India. While epidemics of AVH have been well studied few serious sporadic cases from developing countries have been reviewed. We studied prospectively 75 cases of sporadic AVH who reported to our hospital and were evaluated for the presence of various hepatotropic viruses. The seroprevalence of IgG anti-HEV antibodies was studied in the general population as a control. We found 53.3% (40/75) of sporadic AVH cases were due to hepatitis E virus while 11% (8/75) were due to hepatitis B virus. Hepatitis C virus was responsible for 8% (6/75) of the sporadic AVH cases and hepatitis A was found in 5% (4/75) of the cases. No causative agent was found in 23% (17/75) of the sporadic AVH cases. The sporadic AVH cases due to HEV were not clinically or biochemically not different from AVH due to other viruses. We found a high prevalence of IgG anti-HEV in 35.6% (178/500) among the general population of urban Delhi. The study suggested that hepatitis E was the most common cause of sporadic AVH in urban Delhi. High seroprevalence of IgG anti-HEV antibodies in the general population and amongst the sporadic AVH cases suggests...Continue Reading

Citations

Mar 25, 2015·Case Reports in Hepatology·M PremkumarBadal Kumar
Dec 5, 2008·Journal of Gastroenterology and Hepatology·Masahiko SugitaniMahmud Hasan
Nov 21, 2019·Indian Journal of Medical Microbiology·Arghadip SamaddarSujata Baveja
May 14, 2014·Journal of Medical Microbiology·Nidhi S ChandraDebprasad Chattopadhyay
Dec 3, 2014·The American Journal of Tropical Medicine and Hygiene·Gemechu B GerbiEyasu H Teshale
Mar 26, 2010·The Journal of Antimicrobial Chemotherapy·Florian Bihl, Francesco Negro
Apr 23, 2014·Liver International : Official Journal of the International Association for the Study of the Liver·Manasi MajumdarRadha K Ratho
Jul 6, 2004·Drugs·Harald Claus Worm, Gerhard Wirnsberger
Apr 1, 2019·Indian Journal of Medical Microbiology·Arghadip SamaddarSujata Baveja

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