Role of hyaluronidase in the regulation of functions of mesenchymal precursor cells

Bulletin of Experimental Biology and Medicine
E D GoldbergL A Gur'yantseva

Abstract

The possibility of using hyaluronidase for the regulation of the state of different pools of mesenchymal precursors in vivo was demonstrated. The reaction of mesenchymal precursor cells depended on the dose of the enzyme. Administration of hyaluronidase in a dose of 20 U/mouse increased the content of stromal precursors and mesenchymal stem cells in the bone marrow and promotes mobilization of precursor cells induced by granulocyte CSF. Administration of high dose of hyaluronidase (100 U/mouse) reduced the content of mesenchymal precursors in hemopoietic tissue and abolished granulocyte CSF-induced mobilization of mesenchymal precursor cells of different maturity.

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Dec 27, 2008·Bulletin of Experimental Biology and Medicine·E D GoldbergV V Zhdanov

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Citations

Dec 27, 2008·Bulletin of Experimental Biology and Medicine·A M DygaiE D Goldberg
Jul 19, 2012·Bulletin of Experimental Biology and Medicine·A M DygaiV E Goldberg
Jul 18, 2012·Bulletin of Experimental Biology and Medicine·A M DygaiN N Ermakova
Jul 19, 2012·Bulletin of Experimental Biology and Medicine·A M DygaiD N Kinsht
Mar 14, 2013·Bulletin of Experimental Biology and Medicine·A M DygaiV I Agafonov
Nov 30, 2013·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Dec 10, 2013·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Apr 23, 2008·Journal of Medical Case Reports·Aliye SoyluA Baki Kumbasar
Jun 27, 2015·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Apr 22, 2015·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Mar 18, 2015·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Jan 13, 2015·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai
Jul 18, 2012·Bulletin of Experimental Biology and Medicine·Yu V NesterovaA M Dygai
Jun 3, 2015·Bulletin of Experimental Biology and Medicine·G N Zyuz'kovA M Dygai

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