PMID: 20623953Jul 14, 2010Paper

Role of hyperlipidemia in cholelithiasis

Ėksperimental'nai︠a︡ i klinicheskai︠a︡ gastroėnterologii︠a︡ = Experimental & clinical gastroenterology
I N Grigor'evaM I Voevoda

Abstract

THE PURPOSE OF THE REVIEW: Was analyzed basic data on the contribution of blood serum lipids in the development of gallstone disease (GSD) in the world as well as in northern Russia, as well as the association of cholelithiasis and coronary heart disease (CHD). Worldwide, there is suffer from cholelithiasis 10 to 15% of the population. In Russia, about 60% of adults have a lipid metabolism. According to some epidemiological and clinical studies, serum lipid profile did not differ in patients with and without gallstone disease, in others with cholelithiasis observed hyperlipidemia. In an epidemiological study in the unorganized population of Novosibirsk cholelithiasis occurs more frequently among men and women with lipid disorders. Indigenous peoples of the North Asian Russia this disease is less common than among the aliens, which was accompanied by a more moderate hyperlipidemia. There was a positive association between gallstone disease and coronary heart disease. Despite the fact that hypertriglyceridemia and hypo by a majority of authors are recognized risk factors for gallstone disease, a consensus on the contribution of blood serum lipids in the pathogenesis of gallstone no. Since gallstone mostly composed of cholesterol,...Continue Reading

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