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Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-alpha synthesis: a novel resuscitation strategy

The Journal of Trauma

Nov 19, 2005

R CoimbraD B Hoyt

PMID: 16294063

Abstract

Hypertonic saline (HS) and pentoxifylline (PTX) have been shown to modulate polymorphonuclear neutrophil (PMN) functions after shock and sepsis. We hypothesized that a combination of HS and PTX (HSPTX) would down-regulate PMN functions and inflammatory mediator synthesis more effectivel...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Whole Blood Specimen
Lipopolysaccharides
Biochemical Pathway
ITGAM wt Allele
Tumor Necrosis Factor Production
Neutrophil Activation
Sepsis
Muscle Hypertonia
Neutrophil
Paper Details
References
  • References38
  • Citations15
1234
  • References38
  • Citations15
12

Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-alpha synthesis: a novel resuscitation strategy

The Journal of Trauma

Nov 19, 2005

R CoimbraD B Hoyt

PMID: 16294063

DOI:

Abstract

Hypertonic saline (HS) and pentoxifylline (PTX) have been shown to modulate polymorphonuclear neutrophil (PMN) functions after shock and sepsis. We hypothesized that a combination of HS and PTX (HSPTX) would down-regulate PMN functions and inflammatory mediator synthesis more effectivel...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Whole Blood Specimen
Lipopolysaccharides
Biochemical Pathway
ITGAM wt Allele
Tumor Necrosis Factor Production
Neutrophil Activation
Sepsis
Muscle Hypertonia
Neutrophil

Related Papers

Paper Details
References
  • References38
  • Citations15
1234
  • References38
  • Citations15
12
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