Role of in vivo proton magnetic resonance spectroscopy in the diagnosis and management of brain abscesses

Neurosurgery
R DevM Husain

Abstract

In vivo proton magnetic resonance spectroscopy was performed for 24 patients with pyogenic brain abscesses, to examine the consistency of the spectral patterns and to observe the changes in metabolites with treatment. Localized proton spectra were obtained from 4- to 8-ml volumes in the abscesses, using stimulated echo acquisition mode and spin echo sequences. Twenty-two patients were treated with combined surgical and medical therapy, and two patients were treated conservatively. High-resolution magnetic resonance spectroscopy was performed for 15 samples of abscesses obtained from these patients, to confirm the assignments of resonances seen in vivo. Postaspiration studies were performed for 12 patients treated with combined medical and surgical therapy and 2 patients treated medically. Lactate and amino acids were seen in spectra for all patients, irrespective of the time of spectroscopy after the onset of combined medical and surgical therapy. Acetate and pyruvate disappeared after 1 week of combined treatment. It was concluded that spectral patterns for brain abscesses are consistent and specific and can assist in the noninvasive diagnosis of abscesses. Responses to combined treatment could be monitored by showing the chan...Continue Reading

References

May 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G L MayC E Mountford
Oct 1, 1981·Journal of Neurosurgery·R H BrittA S Yeager
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C RémyA L Benabid

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Citations

Mar 22, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·F BonnevilleJ F Bonneville
Feb 7, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ronan J MurrayTania C Sorrell
Jul 18, 2002·Journal of Neurosurgery·Ozlem Kurtkaya-YapicierJohn E Sawicki
Nov 25, 2003·Journal of Magnetic Resonance Imaging : JMRI·Paul R BurnTimothy P L Roberts
May 28, 2008·Der Radiologe·P PapanagiotouW Reith
Jun 10, 2006·NMR in Biomedicine·Peter B KingsleyRona Woldenberg
Dec 9, 2010·Acta neurochirurgica·Liu-Guan BianJian-Kang Shen
Oct 3, 2009·AJNR. American Journal of Neuroradiology·D PalR K Gupta
Oct 15, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Guanshu LiuPeter C M van Zijl
Feb 5, 2016·NMC Case Report Journal·Alex Roberto Ramírez MejíaManuela Jorquera Moya
Nov 30, 2000·Current Infectious Disease Reports·D P Calfee, B Wispelwey
May 30, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D K YeungC Pang
Nov 30, 2000·Current Treatment Options in Neurology·L E Davis, N G Baldwin
Jan 1, 2005·Topics in Magnetic Resonance Imaging : TMRI·Meng Law
Feb 27, 2010·Neurologia Medico-chirurgica·Tetsuro SameshimaKazuki Nabeshima
Oct 14, 2005·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Keiko Imamura
Aug 27, 2002·Nuclear Medicine Communications·I GoethalsA Signore
Aug 19, 2009·Acta neurochirurgica·Laurence Abeloos, Nicolas Massager
Mar 27, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jing LiuGuanshu Liu
Jun 28, 2011·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Sudheer AmbekarAnitha Mahadevan
Jan 29, 2008·Journal of Neuro-oncology·Yue-Hui MaLi-Jun Wang
Jan 21, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mehdi SasaniAli Fahir Ozer
Oct 12, 2014·Pediatric Radiology·Lynne RuessJerome A Rusin
Oct 7, 2010·Der Radiologe·P PapanagiotouW Reith
Jun 11, 2003·European Journal of Clinical Investigation·M GargR K Gupta
Feb 18, 2016·Journal of Korean Neurosurgical Society·Fatih KeskinHatice Toy
Oct 12, 2000·Magnetic Resonance Imaging·J A SiegalW Perman

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