Role of interleukin-6 (IL-6) in predicting gestational diabetes mellitus

Obstetrics & Gynecology Science
Azam AmirianFatemeh Abdi

Abstract

Gestational diabetes mellitus (GDM) is the most common pregnancy-associated metabolic disorder that is steadily increasing worldwide. Early diagnosis of pregnant women susceptible to GDM is the first step for deploying effective preventive treatment to reduce maternal, fetal, and neonatal complications. The diagnostic process of GDM is still controversial and interleukin-6 (IL-6) is one of the most recent markers used for the diagnosis of GDM. In this study, we aimed to systematically review the role of IL-6 in the diagnosis of GDM. In this systematic review, Google Scholar, Scopus, PubMed, ISI Web of Science, ProQuest, and MEDLINE databases were searched using the following keywords: GDM, screening, and IL-6, with the time interval 2009-2020. The quality of articles was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology checklist. Twenty-four articles with desired quality that met the inclusion criteria were selected and reviewed further. Sixteen studies showed a statistically significant association, while 8 studies did not report any relationship between IL-6 levels and GDM. Based on the results of these studies, assessing the serum IL-6 levels can be investigated a newly established diag...Continue Reading

References

May 2, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Mariusz KuzmickiMaria Gorska
Jul 1, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Abdel Galil M Abdel GaderSitel Banat A Awadallah
Feb 11, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Anne-Sophie MorissetAndré Tchernof
Feb 11, 2011·Diabetes/metabolism Research and Reviews·Maritta Pöyhönen-AlhoR Kaaja
Dec 4, 2012·The Journal of Steroid Biochemistry and Molecular Biology·Daniela VejrazkovaBela Bendlova
Jan 9, 2014·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sümeyra NergizAli Rıza Odabaşı
Jun 7, 2014·Gynecologic and Obstetric Investigation·Şebnem ÖzyerNuri Danışman
Jun 28, 2014·Endokrynologia Polska·Mariusz KuźmickiJacek Szamatowicz
Dec 3, 2014·Diabetes Research and Clinical Practice·C L HarrisonH J Teede
Jan 8, 2015·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·D HassiakosG Chrousos
Sep 27, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Hadi KhodabandehlooReza Meshkani
Apr 12, 2016·Journal of Reproductive Immunology·Andrew S BossickAndrea E Cassidy-Bushrow
Jul 16, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·C SongX Yang
Aug 15, 2017·Diabetes/metabolism Research and Reviews·Sally K AbellHelena J Teede
Aug 29, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Jie ZhangYancheng Xu
Jan 2, 2018·World Journal of Diabetes·AbdelHameed Mirghani Dirar, John Doupis
Mar 15, 2018·Indian Journal of Endocrinology and Metabolism·K A Sudharshana MurthyG Sindhusree
Jul 7, 2018·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Tim Cunningham
Dec 13, 2018·Frontiers in Endocrinology·Evelyn A HuhnChristian S Göbl
Dec 19, 2018·Diabetes Care·UNKNOWN American Diabetes Association
Mar 14, 2019·Archives of Endocrinology and Metabolism·Fernanda Oliveira BragaMarília Brito Gomes
Mar 29, 2019·Obstetrics & Gynecology Science·Fatemeh AbdiFatemeh Sadat Rahnemaie
Jul 25, 2019·Diabetes & Metabolic Syndrome·Samreen SiddiquiShweta Dubey
Jan 4, 2020·Experimental and Therapeutic Medicine·Xueling WangJuan Jiang

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Citations

May 1, 2021·Journal of Clinical Medicine·Delia BogdanetPaula M O'Shea
Aug 31, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Runyu DuLing Li
Sep 4, 2021·The Journal of Clinical Endocrinology and Metabolism·Xinmei HuangJun Liu
Oct 2, 2021·Journal of Cellular Physiology·Lucas Sagrillo-FagundesMárcia R Wink

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

ProQuest
Scopus
Google Scholar

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