PMID: 8969757Dec 1, 1996Paper

Role of interstitial brachytherapy in oral and oropharyngeal carcinoma: reflection of a series of 1344 patients treated at the time of initial presentation

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
M PernotV L Nancy

Abstract

Our study focuses on a series of 1344 cases of carcinoma of the oral cavity and oropharynx treated between 1973 and 1992. Brachytherapy was always performed with iridium 192, either alone or in combination with external-beam irradiation or with surgery for the treatment of the primary tumor. For the oral cavity, we studied 565 cases of mobile tongue. The local control and overall survival rates, respectively, at 5 years are as follows: for T1, 92% and 70%; for T2, 62% and 42%; and for T3, 50% and 29%. For the subgroup T1T2NO, there was a better prognosis for treatment by brachytherapy of the primary lesion alone (p < 0.0001). Two hundred seven cases of floor-of-mouth carcinoma have been reported. The T3T4 patients were not considered surgical candidates. The local control and overall survival rates, respectively, at 5 years are as follows: for T1, 97% and 71%; for T2 72% and 42%; and for T3, 51% and 35%. Ninety-seven patients were treated by postoperative brachytherapy. These were patients for whom the margins after surgery were positive or narrow. A technique termed the modified bridge is described for lesions located in the mandible. Carcinomas of the buccal mucosa are rare in our country; only 42 cases were treated in this c...Continue Reading

References

Apr 1, 1992·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M PernotP Bey
Aug 1, 1990·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·V BenkJ P Le Bourgeois
Dec 1, 1989·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·W M MendenhallR R Million
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Sep 1, 1985·International Journal of Radiation Oncology, Biology, Physics·A A PuthawalaT C Gates
Jun 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M PernotC Marchal

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Citations

Jul 10, 2001·Head & Neck·C G Gourin, J T Johnson
Feb 20, 2009·International Journal of Clinical Oncology·Hitoshi Shibuya
Sep 20, 2005·International Journal of Radiation Oncology, Biology, Physics·Céline BourgierEric Lartigau
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Yoichiro HosokawaMotoyasu Nakamura
Feb 17, 2009·Current Oncology Reports·David N TeguhPaul I M Schmitz
Jan 30, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·S NagN Gupta
Jun 9, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Hidenobu MatsuzakiJun-Ichi Asaumi
Mar 8, 2016·Brachytherapy·Harjot Kaur BajwaKrishnam Raju Alluri
Apr 21, 2009·International Journal of Oral and Maxillofacial Surgery·Y LiJ-Y Lang
Aug 5, 2008·International Journal of Radiation Oncology, Biology, Physics·Ryo-ichi YoshimuraKazuma Toda
Jun 16, 2012·Journal of Medical Imaging and Radiation Oncology·Robert I SmeeJanet Williams
Sep 6, 2002·Acta Oto-laryngologica. Supplementum·Katsuhide InagiHiromi Nagai
Nov 22, 2011·International Journal of Radiation Oncology, Biology, Physics·Ryo-Ichi YoshimuraMasahiko Miura
Jan 9, 2015·Radiation Oncology Journal·Sung Uk LeeChi Young Jeong
Jun 23, 2016·Head & Neck·Jonathan J BeitlerUNKNOWN Expert Panel on Radiation Oncology - Head and Neck
Jul 20, 2011·Journal of Radiation Research·Abulajiang TayierRyoichi Yoshimura
Sep 24, 1999·Hematology/oncology Clinics of North America·S C Marks

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