PMID: 8948485Nov 14, 1996Paper

Role of ionic interactions in cholinesterase catalysis

Biochimica Et Biophysica Acta
V Tõugu, T Kesvatera

Abstract

Acetylcholinesterase (AChE, EC 3.1.1.7) is an enzyme terminating the transmission of nerve impulse in synapses by rapid and selective hydrolysis of the neurotransmitter acetylcholine. Recent years have added a considerable amount of structural knowledge about this protein as well as opened new perspectives to the study of the molecular mechanism of cholinesterase catalysis. In this paper the current state of understanding the molecular recognition by cholinesterases is critically surveyed with particular emphasis on the role of electrostatic interactions.

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Citations

Feb 14, 2012·Molecular Neurobiology·Giselli ScainiEmilio L Streck
May 1, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Cinthia M MazzantiMaria Rosa C Schetinger
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Dec 15, 2012·International Journal of Biological Macromolecules·Karol CiepluchMaria Bryszewska
Dec 4, 2010·European Journal of Pharmacology·Antony SherinCheramadathikudiyil Skaria Paulose
Oct 11, 2012·Neurochemistry International·Gabriela K FerreiraEmilio L Streck
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Feb 6, 2013·European Journal of Pharmacology·Peeyush T KumarCheramadathikudiyil Skaria Paulose
Nov 7, 2016·BMC Pharmacology & Toxicology·Tanara V PeresMichael Aschner
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Feb 5, 2021·The Journal of Physical Chemistry. B·Amit KumawatMasood Ahmad Rizvi
Dec 3, 2020·International Journal of Environmental Research and Public Health·Huihui ChenChristopher J Martyniuk

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