Role of Local Flaps to Achieve Primary Wound Closure in Medication-Related Osteonecrosis of the Jaws Osseous-Resective Surgery

The Journal of Craniofacial Surgery
Antonia MarcianòGiacomo Oteri

Abstract

The aim of the present work is to evaluate the most suitable surgical technique in relation to location and extent of medication-related osteonecrosis of the jaws (MRONJ) through comparison of success rate between the routinely used mucoperiostal flaps and different local flaps designs and propose a standardization of surgical procedures according to MRONJ stage and localization with 2 objectives: to provide the surgeon with an algorithm of treatment according to MRONJ localization and extension; to maximize the success of surgical treatment.Thirteen consecutive patients affected by focal MRONJ were surgically treated with radical osteotomy at the Center for Treatment of the Osteonecrosis of the Jaws (University of Messina, Italy).Initial defects were classified according to the classification of the Italian Societies of Oral Medicine and Maxillofacial Surgery (the SICMF-SIPMO staging system) which consider not only bone exposure but also radiological bone involvement. Treatment outcome was retrospectively assessed according to the different adopted surgical procedure: mucoperiostal flaps (GROUP A) advanced mucoperiostal flaps or rotation flaps (GROUP B) local flaps (GROUP C).Outcome after surgical treatment of focal MRONJ was ...Continue Reading

References

Apr 25, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Eric R Carlson, John D Basile
Apr 21, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·David C Stanton, Edward Balasanian
Jul 18, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Philipp StockmannEmeka Nkenke
Aug 3, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Frank WildeAlexander Hemprich
Oct 12, 2010·Journal of Cancer Research and Clinical Oncology·Thomas MückeFrank Hölzle
Jul 12, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Frank WildeMarcus Heufelder
Dec 7, 2011·Medicina oral, patología oral y cirugía bucal·L GallegoJ Megías
Feb 18, 2012·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Pit Jacob VossRainer Schmelzeisen
Aug 14, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Filippo GrazianiGiuseppe Colella
Feb 1, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Eric R Carlson
May 27, 2014·The British Journal of Oral & Maxillofacial Surgery·Alberto BedogniGiuseppina Campisi
Dec 30, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Horatiu RotaruYoung-Wook Park
Jul 18, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Mattia BerroneMonica Pentenero
Dec 15, 2015·Oral and Maxillofacial Surgery·Larissa Fernandes SilvaMarcos Martins Curi
Jan 7, 2016·Head & Face Medicine·Pit Jacob VossPhilipp Poxleitner
Jan 23, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Jens Philipp BodemChristian Freudlsperger
Feb 10, 2016·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Thomas MückeDenys John Loeffelbein
May 29, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Sarina E C Pichardo, J P Richard van Merkesteyn
Jul 17, 2016·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Sarina E C PichardoJ P Richard van Merkesteyn
Jan 1, 2017·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Hui Young KimByoung Moo Seo
Jul 8, 2017·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Matthias ZirkJoachim E Zöller
Oct 21, 2017·Medicina oral, patología oral y cirugía bucal·T EguchiY Hamada
Nov 7, 2017·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Juliana LemoundNils-Claudius Gellrich
Nov 15, 2017·The Journal of Craniofacial Surgery·Giacomo OteriMarco Cicciù
Apr 11, 2018·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Oliver RistowChristian Freudlsperger
Nov 8, 2018·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Mong-Hun KangSang-Ho Jun

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