Role of MAP1B in axonal retrograde transport of mitochondria

The Biochemical Journal
Eva-María Jiménez-MateosJesús Avila

Abstract

The MAPs (microtubule-associated proteins) MAP1B and tau are well known for binding to microtubules and stabilizing these structures. An additional role for MAPs has emerged recently where they appear to participate in the regulation of transport of cargos on the microtubules found in axons. In this role, tau has been associated with the regulation of anterograde axonal transport. We now report that MAP1B is associated with the regulation of retrograde axonal transport of mitochondria. This finding potentially provides precise control of axonal transport by MAPs at several levels: controlling the anterograde or retrograde direction of transport depending on the type of MAP involved, controlling the speed of transport and controlling the stability of the microtubule tracks upon which transport occurs.

References

May 13, 1977·Brain Research·G A Banker, W M Cowan
Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S T BradyG S Bloom
Nov 1, 1988·Neuron·T Mitchison, M Kirschner
Jan 1, 1986·Annals of the New York Academy of Sciences·L I BinderL I Rebhun
Sep 1, 1986·The Journal of Cell Biology·P W Baas, S R Heidemann
Jan 14, 1994·Brain Research. Developmental Brain Research·M M Oblinger, S A Kost
Apr 15, 1997·Nucleic Acids Research·K ChowdhuryP Gruss
Jul 1, 1996·Frontiers in Bioscience : a Journal and Virtual Library·P J Hollenbeck
Nov 5, 2003·Journal of Neurobiology·Peter W Baas, Daniel W Buster
Oct 7, 2004·Current Opinion in Neurobiology·Nobutaka Hirokawa, Reiko Takemura
Oct 14, 2004·The Journal of Cell Biology·Carolyn J LawrenceLinda Wordeman
Feb 16, 2005·Nature Reviews. Neuroscience·Nobutaka Hirokawa, Reiko Takemura
Mar 15, 2005·The Biochemical Journal·Eva M Jiménez-MateosChristian González-Billault
Mar 25, 2005·Journal of Neuroscience Research·Eva M Jiménez-MateosJesús Avila
Apr 9, 2005·Trends in Cell Biology·Peter W Baas, Liang Qiang
Sep 24, 2005·Journal of Cell Science·Michelle A UttonDiane P Hanger
Nov 25, 2005·Journal of Cell Science·Peter J Hollenbeck, William M Saxton

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Citations

Aug 21, 2007·Nature Cell Biology·Heike StroissniggFriedrich Propst
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ryo YonashiroShigeru Yanagi
Dec 24, 2011·Human Molecular Genetics·Tamar SapirOrly Reiner
Sep 25, 2012·Molecular Neurodegeneration·Keiichi InoueAsa Abeliovich
Nov 24, 2011·PloS One·María Llorens-MartínJesús Avila
Sep 17, 2013·PloS One·Thuy Linh LienVincent Torre
Mar 13, 2014·Journal of Biochemistry·Shun NagashimaShigeru Yanagi
Jan 21, 2014·Cellular and Molecular Life Sciences : CMLS·André Ferreira da SilvaSilvia Campello
Dec 17, 2009·Trends in Cell Biology·Andrew F MacAskill, Josef T Kittler
Jun 11, 2008·Neuroscience Research·Kourosh ShahpasandGholam H Riazi
Sep 7, 2007·Trends in Cell Biology·Istvan R Boldogh, Liza A Pon
Dec 26, 2006·Progress in Neurobiology·Diane T W Chang, Ian J Reynolds
May 23, 2008·Current Opinion in Cell Biology·Sara SalinasGiampietro Schiavo
Jun 26, 2013·Biology of the Cell·Joseph AthertonCarolyn Moores
Feb 11, 2011·Developmental Neurobiology·Gianluca Gallo
Apr 5, 2014·Developmental Neurobiology·David Villarroel-Campos, Christian Gonzalez-Billault
Nov 21, 2009·The EMBO Journal·Anat ShmueliOrly Reiner
Mar 7, 2015·Archives of Toxicology·Daniel José BarbosaFélix Carvalho
Apr 3, 2009·Biochimica Et Biophysica Acta·Zhenyu YueKeiji Tanaka
Jun 7, 2014·Frontiers in Molecular Neuroscience·María Llorens-MartínJesús Avila
Jun 1, 2016·Frontiers in Cellular Neuroscience·Robert F NiescierKyung-Tai Min
Aug 9, 2016·General and Comparative Endocrinology·Xanthe Vafopoulou, Colin G H Steel
Mar 17, 2017·Molecular and Cellular Neurosciences·Omar Loss, F Anne Stephenson
Oct 17, 2017·Developmental Neurobiology·George M Smith, Gianluca Gallo
Mar 2, 2018·CNS Drugs·Alan J Fowler, Charbel E-H Moussa
Jan 6, 2012·Nature Reviews. Neuroscience·Zu-Hang Sheng, Qian Cai
Jan 16, 2008·The Journal of Biological Chemistry·Ben HarrisonTed R Hupp
May 20, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Rodolphe Perrot, Jean-Pierre Julien
Jun 22, 2018·EMBO Reports·Kohei ArasakiMitsuo Tagaya
Mar 23, 2018·Journal of Alzheimer's Disease : JAD·Félix HernándezJesús Avila
Aug 17, 2019·Trends in Cell Biology·Satish BodakuntlaCarsten Janke
Feb 13, 2021·Cells·Ido Rippin, Hagit Eldar-Finkelman

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