Role of milk and dairy intake in cognitive function in older adults: a systematic review and meta-analysis

Nutrition Journal
Jounghee LeeHae-Jeung Lee

Abstract

As aging populations increase across the globe, research on lifestyle factors that prevent cognitive decline and dementia is urgently needed. Therefore, a systematic review was conducted to examine the effects of varying levels of milk intake alone or in combination with other dairy products on the outcomes of cognitive function and disorders in adults. A comprehensive search was conducted across 3 databases (PUBMED, CINAHL, and EMBASE) from their inception through October 2017. Prospective cohort studies and randomized controlled trials (RCTs) that enrolled adults were included. Studies with follow-up durations of less than 4 weeks and studies including schizophrenic patients were excluded. Two independent investigators conducted abstract and full-text screenings, data extractions, and risk-of-bias (ROB) assessments using validated tools. Studies were synthesized qualitatively using a strength of evidence (SoE) rating tool. A random-effects model for meta-analysis was conducted when at least 3 unique studies reported sufficient quantitative data for the same outcome. A total of 1 RCT and 7 cohort studies were included. One medium-quality small RCT (n = 38 participants) showed that only spatial working memory was marginally bet...Continue Reading

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Citations

Nov 16, 2019·Advances in Nutrition·Sujatha RajaramGrace J Lee
Dec 3, 2020·Nutrients·Tommaso FilippiniMarco Vinceti
Nov 19, 2020·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Kenneth RockwoodLindsay M K Wallace
Jan 21, 2021·Molecular Nutrition & Food Research·Araceli Muñoz-GarachUNKNOWN Predimed-Plus Investigators
Apr 9, 2021·The American Journal of Clinical Nutrition·Leah H RubinSheri D Weiser
Jun 17, 2021·Annals of Medicine·Danielle CahoonNanguneri Nirmala
Jun 12, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anne-Julie TessierStéphanie Chevalier
Aug 24, 2021·Frontiers in Psychiatry·Mariana RomanenkoAlexander Vaiserman

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