PMID: 8942377Sep 1, 1996Paper

Role of ocular involvement in the prediction of visual development and clinical prognosis in Aicardi syndrome

The British Journal of Ophthalmology
A V MenezesJ R Buncic

Abstract

This study was undertaken to document visual function and acuity in patients with Aicardi syndrome, and to determine whether there is any relation between ocular features of the syndrome exhibited at birth and later visual function. Fourteen patients with Aicardi syndrome, all examined and followed by the same ophthalmologist, were reviewed between 1975 and 1992 and their ocular characteristics and visual acuity described. It was hypothesised that larger lacunae may be associated with poorer clinical outcome and therefore the relation between these two variables was investigated. Visual acuity as documented by Snellen, Sheridan-Gardner, preferential looking, or pattern visual evoked potential tests was in the normal to low normal range in six eyes of four patients. Visual function correlated significantly with macular appearance. Good visual function was preserved if the fovea appeared normal on funduscopic examination and was uninvolved by lacunae. The size of the largest chorioretinal lacuna also correlated significantly with clinical outcome: patients with large lacunae were more likely to be immobile and to have no language skills. It was concluded that good visual function in patients with Aicardi syndrome may be anticipat...Continue Reading

References

May 1, 1979·Annals of Neurology·J M BertoniR J Allen
Feb 1, 1978·Archives of Ophthalmology·R G WeleberJ B Isom
Feb 1, 1978·Archives of Ophthalmology·C S HoytG Wise
Dec 1, 1979·Australian Paediatric Journal·I J HopkinsE K Turner
Jun 1, 1990·The Journal of Pediatrics·J A NeidichJ M Puck
Aug 30, 1990·The New England Journal of Medicine·R K EymanT L Call
Apr 1, 1989·American Journal of Medical Genetics·A E DonnenfeldB S Emanuel
Nov 1, 1986·Archives of Ophthalmology·R A Del PeroE Torczynski
Jan 1, 1986·Brain & Development·I FerrerJ Campistol
Jan 1, 1985·Brain & Development·N YamamotoT Takeuchi
Feb 1, 1984·Archives of Ophthalmology·R G McMahonS K Ludwin

❮ Previous
Next ❯

Citations

May 2, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Adam S WenickQuan Dong Nguyen
Jan 1, 2009·Human Genetics·Tanya N EbleIgnatia B Van den Veyver
Dec 31, 2002·Pediatric Neurology·Tena L RosserRoger J Packer
Sep 15, 2004·Clinical Dysmorphology·Arpad MatlaryPetter Strømme
Oct 13, 2006·Retina·Diana IturraldeLawrence A Yannuzzi
Nov 28, 2012·Journal français d'ophtalmologie·A TabaryI Drumare-Bouvet
Aug 10, 2011·Pediatric Neurology·Michelle T CabreraElliott H Sherr
Oct 2, 2009·Journal of Pediatric Ophthalmology and Strabismus·Raina GoyalMargaret Hourihan
Jan 9, 2007·Brain & Development·S GrossoP Balestri
Sep 18, 2009·American Journal of Medical Genetics. Part a·Xiaoling WangIgnatia B Van den Veyver
May 24, 2007·Developmental Medicine and Child Neurology·R Melbourne-ChambersM Thame
Jul 15, 2016·PloS One·Mohammed Y AalsalemMuhammad Khurram Khan
Jul 4, 2012·Annals of Saudi Medicine·Erhan BayramHandan Cakmakci
Dec 13, 2006·Journal of Child Neurology·Fatih Mehmet MutluM Zeki Bayraktar
Dec 12, 2018·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Bibiana K Y Wong, V Reid Sutton
Sep 8, 2010·The Journal of Craniofacial Surgery·Maria Carolina OrtubeFederico G Velez
Sep 15, 2005·American Journal of Medical Genetics. Part a·V Reid SuttonIgnatia B Van den Veyver
Nov 28, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Rufina Tin-Yan ChanH Barry Collin
Jan 1, 2009·Fetal and Pediatric Pathology·Thora S SteffensenCurtis E Margo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The British Journal of Ophthalmology
A V MenezesJ R Buncic
The Journal of Pediatrics
P CuratoloB Dallapiccola
Brain & Development
Jean Aicardi
© 2021 Meta ULC. All rights reserved