Role of oxytocin in the control of stress and food intake

Journal of Neuroendocrinology
T Onaka, Y Takayanagi

Abstract

Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake. The oxytocin receptor is located in various brain regions, including the sensory information-processing cerebral cortex; the cognitive information-processing prefrontal cortex; reward-related regions such as the ventral tegmental areas, nucleus accumbens and raphe nucleus; stress-related areas such as the amygdala, hippocampus, ventrolateral part of the ventromedial hypothalamus and ventrolateral periaqueductal gray; homeostasis-controlling hypothalamus; and the dorsal motor complex controlling intestinal functions. Oxytocin affects behavioural and neuroendocrine stress responses and terminates food intake by acting on the metabolic or nutritional homeostasis system, modulating emotional processing, reducing reward values of food intake, and facilitating sensory and cognitive processing via multiple brain regions. Oxytocin also plays a role in interactive actions between stress and food intake and contributes to adaptive active coping behaviours.

References

Mar 1, 1991·Endocrinology·J G VerbalisE M Stricker
Oct 1, 1983·Neuroendocrinology·R E LangW Rascher
Jul 1, 1995·Journal of Neuroendocrinology·S Rivest, N Laflamme
Oct 8, 1996·Regulatory Peptides·E M Stricker, J G Verbalis
Jan 30, 1999·Psychoneuroendocrinology·K Uvnäs-Moberg
Oct 16, 1999·Journal of Neuroendocrinology·M EngelmannC T Wotjak1
Aug 15, 2000·Psychological Review·S E TaylorJ A Updegraff
Jan 4, 2001·Psychosomatic Medicine·G OliverE L Gibson
Mar 29, 2001·Physiological Reviews·G Gimpl, F Fahrenholz
Aug 22, 2001·Peptides·M PeterssonK Uvnäs-Moberg
May 15, 2003·Endocrinology·Rose C MantellaJanet A Amico
Dec 4, 2003·Brain Research·James E BlevinsDenis G Baskin
Mar 27, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·James E BlevinsDenis G Baskin
Mar 27, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Richard J WindleColin D Ingram
Apr 20, 2004·Journal of Neuroendocrinology·J A AmicoX Li
Oct 27, 2005·Proceedings of the National Academy of Sciences of the United States of America·Yuki TakayanagiKatsuhiko Nishimori
Jan 24, 2006·Nature Reviews. Neuroscience·Mike Ludwig, Gareth Leng
Oct 3, 2006·Cell Metabolism·Louise E JohnstoneGareth Leng
Nov 23, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Takefumi KikusuiYuji Mori
Feb 3, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Anthony SclafaniJanet A Amico
May 15, 2007·Neuroreport·Pawel K OlszewskiAllen S Levine
Jun 29, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J A MiedlarJ A Amico
Oct 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Martin Waldherr, Inga D Neumann
Mar 20, 2008·The Journal of Clinical Endocrinology and Metabolism·Tamara Hew-ButlerJoseph G Verbalis
Mar 22, 2008·Endocrinology·Heon-Jin LeeW Scott Young
Apr 17, 2008·The European Journal of Neuroscience·Annegret BlumeInga D Neumann
May 3, 2008·Molecular Endocrinology·Bassil M KublaouiAndrew R Zinn
Jun 4, 2008·Neuroreport·Yuki TakayanagiKatsuhiko Nishimori
Jul 29, 2008·Progress in Brain Research·Gareth LengYuki Takayanagi

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Citations

May 1, 2020·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Adele RomanoSilvana Gaetani
Oct 3, 2020·Frontiers in Human Neuroscience·Alan R Harvey
Apr 25, 2020·Animals : an Open Access Journal From MDPI·Asahi OgiAngelo Gazzano
Jun 6, 2020·Scientific Reports·Shota OkabeTatsushi Onaka
Feb 23, 2020·Frontiers in Neuroscience·Mario CabaMaría J Rovirosa-Hernández
Dec 12, 2020·Physiology & Behavior·Juan Pablo DamiánElize van Lier
Jan 27, 2021·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lily R BarrettXiaobing Zhang
Apr 4, 2021·Pharmaceuticals·Luca BotticelliMaria Vittoria Micioni Di Bonaventura
Apr 9, 2021·Animal Cognition·Marina Victoria DzikMariana Bentosela
Jul 25, 2021·Neuroscience Bulletin·Priscila Vázquez-LeónBruno A Marichal-Cancino
Aug 22, 2021·Current Nutrition Reports·Anica KlockarsPawel K Olszewski
Oct 30, 2021·Journal of Neuroendocrinology·Tatsushi Onaka, Yuki Takayanagi

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Methods Mentioned

BETA
histone acetylation

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