Role of penumbra mechanical thrombectomy device in acute dural sinus thrombosis

The Indian Journal of Radiology & Imaging
Suraj MammenMathew Alexander

Abstract

In dural venous sinus thrombosis (DVST), the mortality ranges 5-30%. Deep venous system involvement and septic dural sinus thrombosis have a higher mortality rate. In acute occlusion, collateral flow may not be established, which may result in significant edema and mass effect. Endovascular interventions may be considered as a treatment option in appropriate high-risk patients with DVST. Eight patients with magnetic resonance imaging (MRI)-confirmed dural sinus thrombosis, who did not respond to the conventional standard medical treatment, were subsequently treated with mechanical thrombectomy using the Penumbra System(®). In all cases, medical treatment including anticoagulants were continued following the procedure for a minimum period of 1 year. Recanalization of the dural sinus thrombosis was achieved in all 8 cases. There were no immediate or late endovascular-related complications. One death occurred due to an unrelated medical event. At 6 months, there was notable improvement in the modified Rankin Score (mRS), with 5/8 (62%) patients achieving mRS of 2 or less. The follow-up ranged between 3 months and 26 months (mean: 14.5 months), and there were no new neurological events during the follow-up period. Cerebral venous s...Continue Reading

References

Apr 18, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·Sanjith AaronAri George Chacko

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Citations

Jun 7, 2018·Journal of Neurointerventional Surgery·Seon-Kyu LeeUNKNOWN Society of NeuroInterventional Surgery
Dec 12, 2020·Scientific Reports·Dagmar KrajíčkováMartin Vališ

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