Role of PIWI-interacting RNAs on cell survival: Proliferation, apoptosis, and cycle.

IUBMB Life
Qian ZengShunlin Qu

Abstract

PIWI-interacting RNAs (piRNAs) are a kind of non-coding small RNAs, which play a biological role by specifically binding to PIWI proteins. Studies have demonstrated that piRNAs play a significant role in germline cell growth by repressing transposable elements, especially in the regulation of DNA methylation. Recently increasing evidence revealed that piRNAs involved in the regulation of cell proliferation, apoptosis, and cycle; however, the mechanism of piRNAs is unclear. This review summarizes the research progress regarding the roles of piRNAs in the cell proliferation, apoptosis, and cycle.

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Citations

Mar 23, 2021·Clinica Chimica Acta; International Journal of Clinical Chemistry·Qian ZengShunlin Qu
Apr 17, 2021·Essays in Biochemistry·Huiwen Yan, Pengcheng Bu
Nov 2, 2021·Bioengineered·Pooneh MokarramHassan Ashktorab

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