PMID: 26327610Sep 4, 2015Paper

Role of preoperative serum creatinine and estimated glomerular filtration rate values in asymptomatic patients undergoing carotid endarterectomy

The Journal of Cardiovascular Surgery
D BissaccoP G Settembrini

Abstract

to evaluate the effect of Chronic Kidney Disease (CKD), assessed by preoperative estimated Glomerular Filtration Rate (eGFR) and serum Creatinine (Cr), on postoperative outcomes and long-term survival in asymptomatic patients undergoing carotid endarterectomy (CEA). We examined data about patients that underwent CEA between January 2002 and September 2014 in our Institution. Retrospective analysis to assess preoperative comorbidities and postoperative complications was performed. Modification of Diet in Renal Disease (MDRD) formula was used to calculate eGFR. Patients were divided into four groups based on values of preoperative eGFR: group A (≥90 mL/min/1.73m2), group B (89-60 mL/min/1.73m2), group C (59-30 mL/min/1.73m2) and group D (≤29 mL/min/1.73m2), and into two groups based on preoperative Cr values: group 1 (<1,5 mg/dL) and group 2 (≥1,5 mg/dL). Primary outcomes were death or the development of one or more postoperative major complications within 30 days after surgery, for each group. Survival curves of Kaplan-Meier were plotted for each group of patients to asses long-term mortality. During the study period, 853 CEAs in 808 patients were performed, of which 682 CEA in 645 patients for asymptomatic carotid artery stenos...Continue Reading

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