Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum

Experimental Brain Research
W Schultz, R Romo


The purpose of these studies was to investigate neuronal activity in the basal ganglia and frontal cortex in relation to the internal generation of goal-directed movements. Monkeys performed goal-directed arm movements at a self-chosen moment in the absence of phasic stimuli providing external temporal reference. They were rewarded with a small morsel of food for each movement, although automatic or repetitive behavior was not reinforced. For reasons of comparison, animals were also trained in a delayed go no-go task in which visual cues instructed them to perform or refrain from an arm movement reaction to a subsequent trigger stimulus. This report describes the activity of neurons in the head of the caudate nucleus and rostral putamen preceding self-initiated arm movements and compares it with instruction-induced preparatory activity preceding movements in the delay task. A total of 497 caudate and 354 putamen neurons were tested in the delay task. Two types of preparatory activity were observed: (1) transient responses to the instruction cue, and (2) sustained activity preceding the trigger stimulus or movement onset. Transient responses were found in 48 caudate and 50 putamen neurons, occurring twice as often in movement ('...Continue Reading


Jun 1, 1978·Electroencephalography and Clinical Neurophysiology·E J NeafseyN A Buchwald
Dec 1, 1977·Journal of the Neurological Sciences·D LaplaneJ M Orgogozo
Jul 9, 1976·Brain Research·H Niki, M Watanabe
Apr 1, 1986·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Feb 1, 1989·Mechanisms of Ageing and Development·M A Babizhayev, M W Brodskaya
Jan 1, 1989·Movement Disorders : Official Journal of the Movement Disorder Society·L E AdlerH Nagamoto
Feb 1, 1989·Brain : a Journal of Neurology·J P DickC D Marsden
Jan 1, 1986·Annual Review of Neuroscience·G E AlexanderP L Strick
Jan 1, 1988·Experimental Brain Research·A NambuK Jinnai
Sep 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·J A Simpson, A J Khuraibet
Jan 1, 1973·Electroencephalography and Clinical Neurophysiology·J TalairachM Rusu
Feb 1, 1973·Experimental Neurology·N A BuchwaldC D Hull
Aug 1, 1984·The Journal of Comparative Neurology·G PercheronC François
Jan 1, 1982·Archiv für Psychiatrie und Nervenkrankheiten·J C Eccles
Jan 1, 1982·Experimental Brain Research·J M MacphersonM Wiesendanger
Jun 20, 1981·The Journal of Comparative Neurology·G W Van HoesenR Lavizzo-Mourey
Nov 1, 1981·Archives of Neurology·G GoldbergJ U Toglia
Mar 8, 1990·The Journal of Comparative Neurology·M F Huerta, J H Kaas

❮ Previous
Next ❯


Mar 24, 1999·Neuroscience and Behavioral Physiology·A A OrlovB F Tolkunov
Mar 18, 2006·Experimental Brain Research·A W MichellR A Barker
Jan 1, 1995·Journal of the Neurological Sciences·D J Brooks
Dec 1, 1993·Current Opinion in Neurobiology·J W Mink, W T Thach
Apr 20, 2004·Neuropsychologia·Hans J C BergerSieberen P van der Werf
Dec 31, 1997·Journal of the Neurological Sciences·I H JenkinsD J Brooks
Jun 12, 2003·Trends in Neurosciences·Wolfram SchultzJeffrey R Hollerman
Apr 28, 1999·Neuroscience·F Dos Santos Villar, J P Walsh
Nov 1, 2012·Proceedings of the National Academy of Sciences of the United States of America·Federico CarnevaleNéstor Parga
Oct 24, 2008·Proceedings. Biological Sciences·Friederike SchlagheckenElizabeth A Maylor
Jun 1, 1997·International Journal of Neural Systems·A Lörincz
Apr 3, 2001·Annual Review of Neuroscience·R Romo, E Salinas
Jun 30, 2007·Annual Review of Neuroscience·Wolfram Schultz
Aug 27, 2010·Journal of Neurophysiology·Michael CamposRichard A Andersen
Jun 13, 2012·Physiology·Alexxai V Kravitz, Anatol C Kreitzer
Jul 11, 2013·Parkinson's Disease·Bubblepreet K RandhawaLara A Boyd
Mar 20, 2001·Neural Computation·R E Suri, W Schultz
Aug 1, 2012·PloS One·Andrey Dovzhenok, Leonid L Rubchinsky
Dec 20, 2012·PloS One·Jessica M Phillips, Stefan Everling
Apr 17, 2004·Journal of Neurosurgery·Nelly Amador, Itzhak Fried
Sep 17, 2014·Progress in Neurobiology·Germán Mendoza, Hugo Merchant
Sep 30, 2014·Nature Neuroscience·Masayoshi MurakamiZachary F Mainen
Dec 1, 1996·Neuropsychologia·K P van SpaendonckA R Cools
Jan 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·L T Robertson, J P Hammerstad
Jun 5, 2008·Proceedings of the National Academy of Sciences of the United States of America·Fernando KasanetzM Gustavo Murer
Dec 5, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mimi H KaoAllison J Doupe
Jan 16, 2009·Journal of Neurophysiology·Joshua D BerkeHoward Eichenbaum
Dec 1, 1993·Current Opinion in Neurobiology·E E Fetz
Jul 10, 2004·Journal of Physiology, Paris·Fadila Hadj-BouzianeDriss Boussaoud
Mar 1, 1995·Behavioural Brain Research·E J Tehovnik
Nov 18, 2010·Experimental Brain Research·Ausaf A FarooquiAditya Murthy
Nov 14, 2000·Trends in Neurosciences·V A Lamme, P R Roelfsema
Apr 28, 2004·NeuroImage·Christina S KonenRüdiger J Seitz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

American Journal of Speech-language Pathology
Susan Rvachew, Barbara May Bernhardt
Frontiers in Computational Neuroscience
Christina M Gremel, Rui M Costa
John D Schlag, Madeleine Schlag-Rey
© 2022 Meta ULC. All rights reserved