Role of qSOFA and SOFA Scoring Systems for Predicting In-Hospital Risk of Deterioration in the Emergency Department.

International Journal of Environmental Research and Public Health
Raúl López-IzquierdoJosé L Martín-Conty

Abstract

The objective of this study was to analyze and compare the usefulness of quick sequential organ failure assessment score (qSOFA) and sequential organ failure assessment (SOFA) scores for the detection of early (two-day) mortality in patients transported by emergency medical services (EMSs) to the emergency department (ED) (infectious and non-infectious). We performed a multicentric, prospective and blinded end-point study in adults transported with high priority by ambulance from the scene to the ED with the participation of five hospitals. For each score, the area under the curve (AUC) of the receiver operating characteristic (ROC) curve was calculated. We included 870 patients in the final cohort. The median age was 70 years (IQR 54-81 years), and 338 (38.8%) of the participants were women. Two-day mortality was 8.3% (73 cases), and 20.9% of cases were of an infectious pathology. For two-day mortality, the qSOFA presented an AUC of 0.812 (95% CI: 0.75-0.87; p < 0.001) globally with a sensitivity of 84.9 (95% CI: 75.0-91.4) and a specificity of 69.4 (95% CI: 66.1-72.5), and a SOFA of 0.909 (95% CI: 0.86-0.95; p < 0.001) with sensitivity of 87.7 (95% CI: 78.2-93.4) and specificity of 80.7 (95% CI: 77.4-83.3). The qSOFA score ca...Continue Reading

References

Oct 30, 2015·BMJ : British Medical Journal·Patrick M BossuytUNKNOWN STARD Group
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Christopher W SeymourDerek C Angus
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Manu Shankar-HariUNKNOWN Sepsis Definitions Task Force
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Mervyn SingerDerek C Angus
Jul 12, 2016·The Journal of Trauma and Acute Care Surgery·Faheem W GuirgisAlan E Jones
Dec 21, 2016·Turkish Journal of Emergency Medicine·Saeed SafariElham Mohammadi
Jan 24, 2017·JAMA : the Journal of the American Medical Association·Eamon P RaithUNKNOWN Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE)
Feb 12, 2017·Internal and Emergency Medicine·Francesca InnocentiRiccardo Pini
Feb 25, 2017·Critical Care : the Official Journal of the Critical Care Forum·Harm-Jan de GroothHeleen M Oudemans-van Straaten
May 17, 2017·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Renata García-GigorroJuan C Montejo-González
Sep 25, 2017·Intensive Care Medicine·Hans FlaattenUNKNOWN VIP1 study group
Sep 15, 2018·The American Journal of Emergency Medicine·Zahra RahmatinejadSaeid Eslami
Sep 30, 2018·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Shahin GainiIsik Somuncu Johansen
Jan 11, 2019·Internal and Emergency Medicine·Francisco Martín-RodríguezRaúl López-Izquierdo
Jun 30, 2019·Canadian Journal of Rural Medicine : the Official Journal of the Society of Rural Physicians of Canada = Journal Canadien De La Médecine Rurale : Le Journal Officiel De La Société De Médecine Rurale Du Canada·Andrew StanleyStefan Grzybowski
Nov 7, 2019·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Jenny KlimpelSirak Petros
Nov 30, 2019·Critical Care : the Official Journal of the Critical Care Forum·Simon LambdenBruno Francois
Dec 21, 2019·Burns : Journal of the International Society for Burn Injuries·Atulya PrasadAdam J Singer

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Citations

Jul 30, 2021·Infection and Drug Resistance·S M Osama Bin AbdullahFinn Erland Nielsen
Oct 15, 2021·International Journal of Immunopathology and Pharmacology·Alaa EfatAly Elkholy

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