PMID: 7538517Jun 1, 1995Paper

Role of radiotherapy in the treatment of epidemic Kaposi's sarcoma: experience with sixty-five cases

Journal of the American Academy of Dermatology
R PiccinnoM Cusini

Abstract

Treatment of Kaposi's sarcoma (KS) associated with HIV infection should improve often disfiguring lesions, with an acceptable cosmetic outcome; relieve associated signs and symptoms (pain and edema); and have no adverse effects on the patient's already impaired immune status. Our purpose was to determine the role of x-ray therapy in the treatment of KS. Contact x-ray therapy and half-deep x-ray therapy were used to treat 594 lesions in 65 patients with KS, who were observed for 1 to 43 months (mean, 9 months). Complete remission was achieved with pigmentation in 405 lesions (68.3%), with good cosmetic results in 105 (17.7%), and with hypopigmentation in three (0.5%). In 80 lesions (13.5%) only size reduction or pain palliation were achieved. Fourteen lesions (2.4%) relapsed 2 to 9 months after treatment. X-ray therapy is well tolerated and meets the specified requirements for the treatment of KS.

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Citations

Mar 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·M J Zalla
Nov 14, 1997·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·N Marchell, T S Alster
Feb 14, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·M CaccialanzaG Eulisse
Jan 1, 1997·Dermatologic Clinics·R R Walther

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