Role of Rapid Diagnostics in Diagnosis and Management of Patients With Sepsis.

The Journal of Infectious Diseases
Taryn A EubankKatherine K Perez

Abstract

Delayed administration of active anti-infective therapy is associated with increased rates of adverse events, mortality, and costs among sepsis patients. Inherent limitations of conventional culture identification methods and the lengthy turnaround time of antimicrobial susceptibility testing are significant barriers to the timely delivery of life-saving therapy, particularly among antibiotic-resistant infections. Culture-independent diagnostic techniques that detect pathogens and antimicrobial resistance genes within clinical samples present a tremendous benefit to timely diagnosis and management of patients. Improved outcomes for rapid intervention with rapid diagnostics have been documented and include decreased mortality rates, decreased health care delivery costs, and faster delivery of appropriate therapeutics.

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Citations

Jul 22, 2020·The Journal of Infectious Diseases·Edward J Septimus
Feb 3, 2021·Joint Commission Journal on Quality and Patient Safety·Sinéad O'DonnellFidelma Fitzpatrick
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Aug 5, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Emily J CurrenL Clifford McDonald

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