PMID: 22352230Feb 23, 2012Paper

Role of red cell distribution width (RDW) in the detection of iron deficiency anaemia in pregnancy within the first 20 weeks of gestation

Bangladesh Medical Research Council Bulletin
G S SultanaA N Ahmed

Abstract

Iron deficiency anemia is common problem during pregnancy. Red cell size variation (anisocytosis) is the earliest morphologic changes in iron deficiency anemia. Red cell distribution width is a quantitative measure of red cell size variation and it can give the idea of early iron deficiency before other test to become positive. 190 pregnant women were included in this study. Red cell distribution width was compared between iron deficient & non-iron deficient pregnant women. Red cell distribution width also compared with Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film in prelatent iron deficiency, latent iron deficiency, mild and moderate iron deficiency anemia. Red cell distribution width had sensitivity 82.3% and specificity 97.4%. Whereas Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film all had 56.6%, 29.2%, 68.1%, 15% and 38.9% sensitivity but specificity was 90.9%, 98.7%, 83.1%, 96.1% and 98.7% in the detection of iron deficiency. Red cell distribution width appears to be a reliable and useful parameter for detection of iron deficiency during pregnancy.

Citations

Dec 5, 2012·Diagnostic Pathology·Esam G AbdelrahmanIshag Adam
Oct 17, 2015·Women's Health·Gian Carlo Di RenzoLuis Cabero Roura
May 9, 2013·International Journal of Laboratory Hematology·A CelikbilekN Tanik
Jul 27, 2018·International Journal of Laboratory Hematology·Shani Levy, Elise Schapkaitz
Dec 26, 2015·The Neurologist·Egilius L H Spierings, Thomas D Sabin
Jul 4, 2020·Critical Reviews in Food Science and Nutrition·Mauricio Restrepo-GallegoPatrícia H C Rondó
May 28, 2019·Fetal and Pediatric Pathology·Mullapudi Venkata SurekhaPutcha Uday Kumar
Nov 16, 2018·Biochemia Medica·Panagiotis PaliogiannisCiriaco Carru
May 18, 2021·Obstetric Medicine·Sona M VoraSue Pavord

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