Role of Resection in Glioblastoma Management.

Neurosurgery Clinics of North America
Mark W YoungbloodAdam M Sonabend

Abstract

Whenever possible, maximal safe resection is the first intervention for management of glioblastoma. Resection offers tissue for diagnosis, decompression of the brain, cytoreduction, and has been associated with prolonged survival in numerous retrospective studies. In this review, we provide a critical overview of the literature associating glioblastoma resection with survival. We discuss techniques that enhance extent of resection, and the role of clinical and surgeon-variables. At last, we analyze the covariates and confounders that might influence the relationship between extent of resection and survival for glioblastoma, as these might ultimately also influence outcomes and other therapeutic interventions tested in trials.

Citations

Sep 29, 2021·Neuro-oncology·Massimiliano Del BeneGiuliana Pelicci

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Stem Cells in Glioblastoma

Glioblastoma is the most common and aggressive type of brain tumor. It contains a population of tumor initiating stem cell-like cells known as cancer stem cells. Investigations are ongoing into these cancer stem cells found in these solid tumors which are highly resistance to treatment. Here is the latest research on cancer stem cells in glioblastoma.

Related Papers

Journal of Neurological Surgery. Part A, Central European Neurosurgery
Victoria WykesColin Watts
The Cancer Journal
Stephen J Hentschel, Frederick F Lang
Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Mark BloomstonE Christopher Ellison
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Emily A FerencziAaron L Berkowitz
© 2021 Meta ULC. All rights reserved