PMID: 1684731Sep 27, 1991Paper

Role of the alpha 1- and alpha 2-adrenoceptors of the lateral hypothalamus in the dipsogenic response to central angiotensin II in rats

Brain Research
A C FerrariJ V Menani

Abstract

The present experiments were conducted to investigate the role of the alpha 1- and alpha 2-adrenergic receptors of the lateral hypothalamus (LH) on the drinking response elicited by intracerebroventricular (i.c.v.) injections of carbachol and angiotensin II (AII) in rats. Clonidine (an alpha 2-adrenergic agonist) injected into the LH produced a dose-dependent reduction of the drinking responses elicited by i.c.v. administration of carbachol and AII. The alpha 1-adrenergic agonist phenylephrine injected into the LH reduced the dipsogenic response to i.c.v. AII, but not to carbachol. Injection of yohimbine (an alpha 2-adrenergic antagonist) and prazosin (an alpha 1-adrenergic antagonist) into the LH also reduced the water intake produced by i.c.v. injection of AII. Previous injection of alpha 1- or alpha 2-adrenergic antagonists into the LH increased the antidipsogenic effect of clonidine or phenylephrine injected into the same area on the water intake induced by i.c.v. AII. These results show that the alpha 1- and alpha 2-adrenergic receptors of the LH are involved in the control of drinking responses elicited by i.c.v. injection of AII in rats. They also show that clonidine, but not phenylephrine, suppresses the drinking induce...Continue Reading

References

Aug 1, 1990·Pharmacology, Biochemistry, and Behavior·E ColombariJ V Menani
Sep 1, 1970·The Journal of Physiology·A N EpsteinB J Rolls
Jan 1, 1971·Pharmacology·W B SeversJ D Connor
Oct 13, 1972·Brain Research·J B Simpson, A Routtenberg
Apr 30, 1984·Brain Research·M J FreglyJ E Greenleaf
Apr 1, 1984·Brain Research Bulletin·M J FreglyJ E Greenleaf
Mar 1, 1984·Appetite·K M WilsonM J Fregly

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Citations

Feb 9, 2010·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Ali BaghbanzadehReza Maleklou
Sep 1, 1993·Pharmacology, Biochemistry, and Behavior·J C CalleraW A Saad
Jan 1, 1996·Neuroscience and Biobehavioral Reviews·L L Bernardis, L L Bellinger
Oct 2, 2003·European Journal of Pharmacology·Shahrbanoo OryanBehrooz Kohanrooz
Nov 12, 2002·Brain Research·Lisandra Oliveira MargathoJosé Vanderlei Menani
May 1, 1997·Pharmacology, Biochemistry, and Behavior·M M YadaL A de Luca Júnior
Jan 1, 1997·Brain Research Bulletin·M M YadaL A De Luca
Jul 29, 1999·Brain Research Bulletin·J V MenaniL A De Luca
Aug 23, 2001·Autonomic Neuroscience : Basic & Clinical·T S MoreiraJ V Menani
Aug 1, 2014·The Journal of Physiological Sciences : JPS·Morteza Zendehdel, Shahin Hassanpour
Jan 1, 1995·Clinical and Experimental Hypertension : CHE·T A JenkinsF A Mendelsohn
Apr 28, 2016·Physiology & Behavior·Makoto Takahashi, Junichi Tanaka
Aug 20, 2002·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·W A SaadWillian A Saad
Apr 1, 1997·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·L A De-Luca Júnior, J V Menani
Jan 10, 2014·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jose V MenaniAlan Kim Johnson

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