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Role of the GroEL chaperonin intermediate domain in coupling ATP hydrolysis to polypeptide release

The Journal of Biological Chemistry

Apr 29, 1998

J Martin

PMID: 9516431

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Abstract

Modification of the Escherichia coli chaperonin GroEL with N-ethylmaleimide at residue Cys138 affects the structural and functional integrity of the complex. Nucleotide affinity and ATPase activity of the modified chaperonin are increased, whereas cooperativity of ATP hydrolysis and aff...read more

Mentioned in this Paper

Ethylmaleimide
GroEL Protein
HSPD1 gene
Alkalescens-Dispar Group
Structure-Activity Relationship
HSPE1 gene
Crystallography, X-Ray
Chaperone Activity
Sulfhydryl Reagents
Protein Conformation
Paper Details
References
  • References26
  • Citations5

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The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.

Chaperones & Protein Folding

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.

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Role of the GroEL chaperonin intermediate domain in coupling ATP hydrolysis to polypeptide release

The Journal of Biological Chemistry

Apr 29, 1998

J Martin

PMID: 9516431

DOI:

Abstract

Modification of the Escherichia coli chaperonin GroEL with N-ethylmaleimide at residue Cys138 affects the structural and functional integrity of the complex. Nucleotide affinity and ATPase activity of the modified chaperonin are increased, whereas cooperativity of ATP hydrolysis and aff...read more

Mentioned in this Paper

Ethylmaleimide
GroEL Protein
HSPD1 gene
Alkalescens-Dispar Group
Structure-Activity Relationship
HSPE1 gene
Crystallography, X-Ray
Chaperone Activity
Sulfhydryl Reagents
Protein Conformation

Feeds With Similar Papers

ASBMB Publications

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.

Chaperones & Protein Folding

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.

Related Papers

Paper Details
References
  • References26
  • Citations5

Download from

PubMed
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