Role of the patient comorbidity in the recurrence of chronic subdural hematomas.

Neurosurgical Review
Rafael Martinez-PerezAlfonso Lagares

Abstract

Chronic subdural hematoma (CSDH) is an old blood collection between the cortical surface and the dura. Recurrence of CSDH after surgical evacuation occurs in up to a quarter of patients. The association between patient premorbid status and the rate of recurrence is not well known, and some previous results are contradictory. We aim to determine the impact of patient comorbidities in the risk of recurrence after surgical evacuation of CSDH. Retrospective data of a single institution's surgically evacuated CSDH cases followed up for at least 6 months were analyzed, and univariate and multivariate analyses were performed to identify the relationships between recurrence of CSDH and factors such as age, gender, CSDH thickness, neurological impairment at admission (NIHSS score), location of the CSDH (unilateral vs bilateral), Charlson Comorbidity Index (CCI), prothrombin time (PT), hemoglobin levels, and platelet count. A total of 90 patients (71 men and 19 women), aged 41-100 years (mean age, 76.4 ± 11.2 years), were included. CSDH recurred in 17 patients (18.9%). A higher CCI correlated with higher scores in the NIHSS. In the univariate analysis, recurrence was associated with a higher CCI (2.39 vs 1.22, p = 0.002), higher NIHSS sc...Continue Reading

References

Mar 1, 1995·Journal of the American Geriatrics Society·C J RozzelleC L Branch
Jun 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·R WeigelJ K Krauss
Feb 2, 2013·Surgical Neurology International·Danilo Otávio de Araújo SilvaHildo Rocha Cirne de Azevedo Filho
Aug 12, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Henri-Arthur LeroyJean-Paul Lejeune
May 28, 2016·Journal of Neurosurgery·Yasuaki AbeYoshiaki Shiokawa
Mar 23, 2017·Neurosurgery Clinics of North America·Wuyang Yang, Judy Huang
Dec 6, 2018·Trials·Angelos G KoliasUNKNOWN British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators
Jun 20, 2019·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Shen WangJunfeng Feng
Aug 27, 2019·World Neurosurgery·Lun-Xin LiuChao-Hua Yang

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