PMID: 8150265Feb 15, 1994

Role of the phosphotransferase system in Escherichia coli strains deficient in hexose phosphate transport

FEMS Microbiology Letters
Valérie Dumay, Martine Crasnier


In Escherichia coli, glucose 6-phosphate is transported via the Uhp system which is inducible by glucose 6-phosphate. We showed that, in a uhp-deficient strain, glucose 6-phosphate was dephosphorylated in the periplasm and that the resulting glucose was subsequently transported into the cells via the phosphotransferase system. The uptake of glucose generated from glucose 6-phosphate allowed the bacteria to produce an increased level of cAMP compared to cells grown on non-limiting concentrations of glucose.


Oct 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·A UllmannJ Monod
Mar 1, 1977·Journal of General Microbiology·R C Essenberg, H L Kornberg
Nov 1, 1969·Journal of Bacteriology·B TylerB Magasanik
Dec 1, 1971·Journal of General Microbiology·D G MaclennanN T Cotton
Mar 1, 1980·Journal of Bacteriology·A W RephaeliM H Saier
Mar 18, 1961·Biochimica Et Biophysica Acta· von HOFSTEN


Jun 27, 1998·Molecular Microbiology·B M HogemaPieter W Postma

Related Concepts

UhpA protein, Bacteria
UhpA protein, E coli
Acid Phosphatase
Cyclic AMP, (R)-Isomer
Adenylate Cyclase
Alkaline Phosphatase
Bacterial Proteins
DNA Transposons
DNA Helix Destabilizing Proteins
DNA, Bacterial

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