PMID: 3537616Jan 1, 1986

Role of the toxicology laboratory in the treatment of acute poisoning

Medical Toxicology
B R HeplerI Sunshine


The modern toxicology laboratory can play an important role in the evaluation of poisoning. In order to appreciate the nature and extent of this role, several essential elements necessary to an acute care toxicology service should be considered. When an ongoing and effective dialogue between clinicians and the toxicology laboratory staff is established, and a broadly based analytical approach is applied to the analysis of the appropriate biological fluids, a dynamic and viable toxicology service will result. How these elements work together to facilitate this service will be discussed, based primarily on experience in a large teaching hospital. This experience indicates that if the elements necessary to provide laboratory support in the investigation of an alleged poisoning are in place, the toxicology laboratory plays an important role in ensuring optimum and effective patient care.


Oct 6, 1979·British Medical Journal·M HelliwellR J Flanagan
May 1, 1985·Journal of Analytical Toxicology·D W JonesR J Rousseau
Jul 1, 1985·Journal of Analytical Toxicology·C A SutheimerI Sunshine
May 1, 1974·Journal of Chromatographic Science·C B WalbergV A Pantlik
May 26, 1972·Biochemical and Biophysical Research Communications·K E RubensteinE F Ullman
Mar 1, 1971·Clinical Toxicology·W J Decker, J J Treuting
Jan 1, 1981·Annals of Emergency Medicine·A R Soslow
Jun 1, 1982·American Journal of Clinical Pathology·C A SutheimerI Sunshine
Mar 1, 1983·Journal of Analytical Toxicology·C A SutheimerI Sunshine
Sep 1, 1984·The American Journal of Emergency Medicine·J C Veltri, T L Litovitz
Jul 1, 1983·Acta paediatrica Scandinavica·D JacobsenA F Bakken
Jan 1, 1984·Toxicology Letters·P Arvela, A J Jounela
Jul 1, 1983·Archives of Disease in Childhood·A W Craft
Jun 1, 1982·Journal of Toxicology. Clinical Toxicology·B R HeplerI Sunshine
Sep 1, 1982·Journal of Analytical Toxicology·B R HeplerM W Konstan
May 1, 1981·Clinical Pharmacology and Therapeutics·J A IngelfingerP Goldman
Nov 1, 1981·Journal of Analytical Toxicology·J G Rio, C N Hodnett
Jul 1, 1980·Journal of Analytical Toxicology·D N Bailey, A S Manoguerra


Dec 4, 2004·Clinical Chemistry and Laboratory Medicine : CCLM·Steve George

Related Concepts

Laboratory Diagnosis

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Related Papers

Journal of Toxicology. Clinical Toxicology
B R HeplerI Sunshine
Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
Kavitha SaravuJagadeswara Rao Earla
© 2021 Meta ULC. All rights reserved