Role of the upper airways in patients with chronic cough

Current Opinion in Allergy and Clinical Immunology
Eva Millqvist, Mats Bende

Abstract

Chronic cough can be caused by a number of factors, including infections, rhinosinusitis, asthma and environmental stimuli. This paper reviews recent findings and opinions regarding the role played by the upper airways in chronic cough. Chronic cough has a significant impact on quality of life, which is more pronounced in women. In Western countries, the reported occurrence of rhinosinusitis in patient groups with chronic cough ranges from 8% to 81%. Allergic rhinitis is a risk factor for later development of asthma. In children, bronchiectasis is combined with upper airway abnormalities in the majority of cases. Increased expression of the capsaicin receptor subtype named 'transient receptor potential vanilloid-1', which correlates with capsaicin cough response, has been identified in patients with chronic cough. Patients with airway chemical sensitivity and chronic cough as one symptom have augmented capsaicin cough sensitivity that is related to changed levels of nerve growth factor in nasal lavage. Involvement of the upper airways in chronic cough has been confirmed in several studies. However, there are considerable differences between different health centres in the occurrence of rhinosinusitis as a cause of chronic cough...Continue Reading

References

May 15, 1998·International Archives of Occupational and Environmental Health·J E Cometto-Muñiz, W S Cain
Nov 27, 2002·Journal of Occupational and Environmental Medicine·Ewa Ternesten-HasséusEva Millqvist
May 14, 2003·The Journal of Allergy and Clinical Immunology·Andrew Szczeklik, Donald D Stevenson
Dec 6, 2003·American Journal of Respiratory and Critical Care Medicine·Peadar G NooneMichael R Knowles
Mar 9, 2004·The Journal of Physiology·Brendan J CanningBradley J Undem
Mar 17, 2004·International Archives of Occupational and Environmental Health·Steven NordinMats Bende
Apr 15, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E MillqvistM Bende
Apr 28, 2004·Experimental Brain Research·J Enrique Cometto-MuñizMichael H Abraham
Jul 3, 2004·Allergy·C RaherisonUNKNOWN SPLF Working Group "Nez-Bronches"
Aug 19, 2004·European Journal of Gastroenterology & Hepatology·Philip J MatthewsPraveen Anand
Sep 11, 2004·The European Respiratory Journal·A H MoriceUNKNOWN ERS Task Force
Sep 28, 2004·American Journal of Respiratory and Critical Care Medicine·David A GronebergK Fan Chung
Nov 27, 2004·Pulmonary Pharmacology & Therapeutics·K F Chung, J G Widdicombe
Nov 27, 2004·Pulmonary Pharmacology & Therapeutics·Alyn H Morice
Nov 27, 2004·Pulmonary Pharmacology & Therapeutics·Stuart B Mazzone
Nov 27, 2004·Pulmonary Pharmacology & Therapeutics·Michael J Carr
Jan 12, 2005·Current Opinion in Allergy and Clinical Immunology·Jonathan M Spergel
Feb 3, 2005·The European Respiratory Journal·J A KastelikA H Morice
Mar 23, 2005·Archives of Otolaryngology--head & Neck Surgery·Xinjing WangGarry R Cutting
May 13, 2005·Chest·Rubaiyat A HaquePeter J Barnes
Jul 8, 2005·International Archives of Occupational and Environmental Health·A JohanssonM Bende
Jul 9, 2005·Chest·Peter V Dicpinigaitis, Rakesh V Alva
Jul 23, 2005·Ultrastructural Pathology·Birgitta Carlén, Unne Stenram

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Citations

Apr 19, 2011·Current Opinion in Otolaryngology & Head and Neck Surgery·Ryan PalmerPhil Gallagher
Nov 5, 2013·Journal of Pharmaceutical Sciences·Ying FanChandrahas G Sahajwalla
Aug 3, 2013·Pediatric Clinics of North America·Naren N VenkatesanMichael Underbrink
Dec 30, 2008·Pulmonary Pharmacology & Therapeutics·Milos TatarMarian Kollarik
Dec 17, 2009·Respiratory Medicine·J B WateletG Brusselle
May 29, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marta DąbrowskaRafał Krenke

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