Role of thyroid hormones in human and laboratory animal reproductive health

Birth Defects Research. Part B, Developmental and Reproductive Toxicology
Neepa Y ChoksiMichael Shelby

Abstract

The highly conserved nature of the thyroid gland and the thyroid system among mammalian species suggests it is critical to species survival. Studies show the thyroid system plays a critical role in the development of several organ systems, including the reproductive tract. Despite its highly conserved nature, the thyroid system can have widely different effects on reproduction and reproductive tract development in different species. The present review focuses on assessing the role of thyroid hormones in human reproduction and reproductive tract development and comparing it to the role of thyroid hormones in laboratory animal reproduction and reproductive tract development. The review also assesses the effects of thyroid dysfunction on reproductive tract development and function in humans and laboratory animals. Consideration of such information is important in designing, conducting, and interpreting studies to assess the potential effects of thyroid toxicants on reproduction and development.

References

Jan 1, 1979·Pharmacology & Therapeutics. Part B: General & Systematic Pharmacology·K D DöhlerA von zur Mühlen
Jul 1, 1992·Endocrinology·M RodríguezT Jolin
Jul 26, 1991·Biochimica Et Biophysica Acta·L SavuI L Flink
Nov 13, 1987·Biochemical and Biophysical Research Communications·L SavuE A Nunez
Aug 1, 1989·Clinical Nuclear Medicine·M A AntarR P Spencer
Dec 1, 1985·Endocrinology·A Perez-CastilloT Pans
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·I L FlinkE Morkin
Oct 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A Kawaoi
Nov 1, 1987·Journal of Steroid Biochemistry·C BourgetC Longcope
Mar 19, 1981·The New England Journal of Medicine·D A Fisher, A H Klein
Sep 1, 1982·Early Human Development·A H KleinD A Fisher
Dec 1, 1993·Molecular and Cellular Endocrinology·A Tsykin, G Schreiber
May 1, 1996·Journal of Molecular and Cellular Cardiology·L D MetzT A Slotkin
Jul 29, 1998·Environmental Health Perspectives·R N HillD V Singh
Oct 20, 1998·Thyroid : Official Journal of the American Thyroid Association·F Brucker-Davis
Oct 19, 1999·Thyroid : Official Journal of the American Thyroid Association·M AbalovichS Gutierrez
Feb 24, 2000·Biology of Reproduction·J J BuzzardN G Wreford
Apr 6, 2000·The Journal of Endocrinology·S Chan, M D Kilby
May 17, 2000·Acta medica Austriaca·J Köhrle
Sep 22, 2000·The Journal of Clinical Endocrinology and Metabolism·E A JanniniM D'Armiento
Oct 6, 2000·General and Comparative Endocrinology·D M PowerC R Santos
Dec 20, 2000·Fertility and Sterility·G E Krassas
Aug 22, 2001·Biology of Reproduction·S M Mendis-Handagama, H B Ariyaratne
Nov 21, 2001·Toxicology and Applied Pharmacology·N R Vansell, C D Klaassen
Nov 22, 2001·Current Opinion in Pediatrics·M P Gillam, P Kopp
Aug 6, 2002·The Journal of Clinical Endocrinology and Metabolism·G E KrassasK Miras
Aug 8, 2002·Thyroid : Official Journal of the American Thyroid Association·Clare B Harvey, Graham R Williams
Dec 12, 2002·The Journal of Endocrinology·P J O'Shea, G R Williams
May 30, 2003·Reproduction : the Official Journal of the Society for the Study of Fertility·Richard M SharpeJane S Fisher
Feb 1, 1958·The American Journal of Physiology·J D FELDMAN
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·C D Karabinas, G J Tolis

Citations

Oct 31, 2014·Expert Review of Molecular Diagnostics·Stephan BeiskenReza M Salek
Nov 5, 2011·Regulatory Toxicology and Pharmacology : RTP·Shakil A SaghirEdward W Carney
Mar 24, 2015·The Journal of Reproduction and Development·Lingfa KongGen Watanabe
Jun 28, 2008·Toxicology Letters·Shakil A SaghirAmy J Clark
Mar 21, 2007·Brain Research·George StoicaJohn T Jaques
Feb 25, 2005·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Gloria D JahnkeMichael D Shelby
Apr 6, 2011·Environmental Toxicology and Chemistry·Richard R BernhardtTodd M O'Hara
Nov 21, 2015·Animal : an International Journal of Animal Bioscience·F M McGovernT M Boland
Mar 31, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·David Y LaiWolfgang Dekant
Mar 11, 2015·General and Comparative Endocrinology·Christoff G FurinTodd M O'Hara
Dec 21, 2014·Regulatory Toxicology and Pharmacology : RTP·Joanne A LasradoKelli A Herrlinger
May 7, 2016·Toxicology Letters·Jeff R FowlesArlean M Rohde
May 26, 2016·Environmental Science and Pollution Research International·Doha M BeltagyEhab Tousson
Jan 11, 2016·Acta Physiologica·D GnocchiP Parini
May 14, 2010·Experimental Biology and Medicine·Branka Sosić-JurjevićMilka Sekulić
Jan 24, 2017·Laboratory Investigation; a Journal of Technical Methods and Pathology·Junguee LeeMinho Shong
Feb 11, 2016·Human & Experimental Toxicology·Thomas G OsimitzA Wallace Hayes
Feb 28, 2018·Experimental Physiology·Fatemeh BagheripuorAsghar Ghasemi
May 17, 2018·Biology of Reproduction·Juneo F SilvaRogéria Serakides
Sep 16, 2015·Environmental Health Perspectives·Colleen M MakeyThomas F Webster
Aug 2, 2008·The Journal of Toxicological Sciences·Ena LeeHyung Sik Kim
Sep 5, 2019·Naunyn-Schmiedeberg's Archives of Pharmacology·Mona Abdel-RahmanSafia Essam
Sep 12, 2019·Journal of Applied Toxicology : JAT·Kirt R PhippsPascale Fança-Berthon
Dec 13, 2019·Toxicologic Pathology·June K DunnickArun R Pandiri
Apr 29, 2020·Journal of Applied Toxicology : JAT·Timur DurraniDennis Shusterman
Mar 26, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·I Y OzdemirM Ozturk
Jun 18, 2020·Toxicology and Industrial Health
Jul 16, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Xueying HanDeqiang Dou
Sep 25, 2017·Endocrinology·Kazuyoshi TsutsuiIchiro Miyata
Oct 8, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·E BerardescaM Marinovich
Sep 17, 2020·Brazilian Journal of Biology = Revista Brasleira De Biologia·D S Foda, S G Shams
Apr 23, 2017·Scientific Reports·Mika KiyoharaKazuyoshi Tsutsui
May 22, 2017·Archives of Toxicology·Gregory G Bond, Daniel R Dietrich
Apr 8, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Tai-Yuan ChuangChung-Hsin Wu
Aug 31, 2017·Journal of Animal Science and Biotechnology·Marcos Eli BuzanskasDanísio Prado Munari
Dec 8, 2017·Animal Science Journal = Nihon Chikusan Gakkaihō·Quanwei WeiFangxiong Shi
Nov 8, 2019·Toxicological Sciences : an Official Journal of the Society of Toxicology·Iman HassanMary E Gilbert
Jan 14, 2020·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Helena KerpDagmar Führer
Aug 18, 2020·Regulatory Toxicology and Pharmacology : RTP·Christian StruppPramila Singh
Mar 10, 2020·Molecular and Cellular Endocrinology·Stephan CouderqJean-Baptiste Fini

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