Role of transbronchial biopsies in pediatric lung diseases

Chest
Gary VisnerDani S Zander

Abstract

To evaluate the role of transbronchial biopsies (TBBs) in pediatric lung diseases. We reviewed the records of TBBs performed in pediatric patients at the University of Florida between July 1996 and August 2003. The sample adequacy, diagnostic utility, and procedural complications of the two types of bronchoscopy apparatuses used to collect the samples were assessed and compared. A total of 429 TBB procedures were performed in 46 patients (age range, 2 months to 21 years) who had received a heart-lung or lung transplant and in 38 non-lung transplant patients (age range, 2 weeks to 18 years). For 86 procedures, the pediatric bronchoscope and forceps that fit in a 1.2-mm channel were used, and a small adult bronchoscope and 2.0-mm forceps were used for the remaining procedures. Adequate tissue samples were obtained in 85% of the procedures using a pediatric bronchoscope and in 97% using an adult bronchoscope. In the non-lung transplant patients, the biopsy findings were considered to be diagnostic in 58% of all procedures (adult bronchoscope, 64%; and pediatric bronchoscope, 50%), contributory in 21%, and noncontributory in 21%. In the lung transplant patients, treatable acute cellular rejection was diagnosed in 24% of the surveil...Continue Reading

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Citations

Jul 21, 2004·Journal of Endourology
Sep 2, 2006·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Claire LangstonFrances White
Jan 31, 2008·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Megan K DishopFrances V White
Aug 3, 2013·American Journal of Respiratory and Critical Care Medicine·Geoffrey KurlandUNKNOWN American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network
May 6, 2015·Pediatric Pulmonology·Jackson Y WongGregory I Snell
May 24, 2011·Archivos de bronconeumología·Javier Pérez-FríasUNKNOWN Sociedad Española de Neumología y Cirugía Torácica
Nov 18, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A FaroUNKNOWN American Society of Transplantation
Jul 10, 2013·Pediatric Pulmonology·Christopher R GilbertLonny Yarmus
Mar 8, 2016·Expert Review of Respiratory Medicine·P Goussard, R P Gie
Sep 28, 2010·The Annals of Thoracic Surgery·Samuel B GoldfarbGary Visner
Feb 3, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·K BochennekT Lehrnbecher
Jul 30, 2016·Pediatric Clinics of North America·Albert Faro, Alexander Weymann
Apr 1, 2010·Journal of Bronchology & Interventional Pulmonology·Hamidreza JabbardarjaniMohammad Reza Masjedi
Dec 16, 2017·The European Respiratory Journal·Ernst EberFabio Midulla
Feb 16, 2008·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jonathan M MansbachCarlos A Camargo
Oct 19, 2019·American Journal of Respiratory and Critical Care Medicine·Jennifer M BousoJoseph Piccione
Nov 28, 2020·Respiratory Medicine·Biplab K Saha
Oct 5, 2021·Expert Review of Respiratory Medicine·Mohammad Ashkan Moslehi

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