Role of transurethral resection in dissemination of cancer of prostate

Urology
E S LevineE L Cohen

Abstract

Recent studies have suggested an adverse impact on disease progression and survival in patients with prostatic cancer who undergo transurethral resection (TURP). Four hundred fifteen patients with prostatic carcinoma were reported to a Tumor Registry from 1965 to 1971. Of these, 184 charts had sufficient follow-up data to assess the impact of TURP in each stage of prostatic cancer. In Stage A the five-year survival difference between the TURP group (87.5%) and the open prostatectomy group (88%) was not significant (P = 0.54). In Stage B the five-year survival difference between the TURP group (38.7%) and the needle biopsy group (68%) was significant (P = 0.02). In Stages C and D there was no significant difference in survival between the TURP group and the needle biopsy group (P = 0.44 and P = 0.2, respectively). Our data reinforce the importance of diagnosing Stage B prostatic cancer preoperatively when curative treatment modalities may be utilized and TURP avoided. Finally, in advanced stages TURP may be efficacious in relieving prostatic obstruction while not adversely influencing survival.

References

Jun 15, 1983·Cancer·G W Jones
Sep 1, 1980·International Journal of Radiation Oncology, Biology, Physics·D G McGowan

❮ Previous
Next ❯

Citations

Apr 27, 2007·Current Urology Reports·Jason W AnastRobert L Grubb
Nov 10, 2012·Clinical Genitourinary Cancer·Masaru Morita, Takeshi Matsuura
Oct 13, 2006·BJU International·Martin MarszalekStephan Madersbacher
Sep 17, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Luigi Mearini
May 1, 2021·Journal of Personalized Medicine·Katalin BalázsKatalin Lumniczky
Nov 1, 1989·International Journal of Radiation Oncology, Biology, Physics·S O AsbellC A Perez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.