Roles and mechanisms of ginsenoside in cardiovascular diseases: progress and perspectives

Science China. Life Sciences
Yingying SunKeji Chen

Abstract

Ginseng is among the oldest traditional Chinese medicinal herbs and is widely used in China and Southeast Asia. Over the past 50 years, considerable research has focused on the chemical constituents, pharmacological action, and clinical applications of ginseng. In this review, we examine the current state of research on ginseng, including the main active ingredient ginsenoside, its pharmacological effects on the cardiovascular system, and mechanisms of action. We focus on what is known of the effects of ginseng against atherosclerosis, arrhythmia, myocardial ischemia, and its inhibition of ventricular remodeling, providing a basis for expanding the clinical applications of ginseng.

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Citations

Nov 7, 2017·Nucleic Acids Research·Lin HuangChengping Wen
Nov 22, 2017·PeerJ·Abdelrahman ElshafayNguyen Tien Huy
Feb 2, 2018·BioMed Research International·Meng-Meng ZhengXue-Lan Zhang
Feb 23, 2019·Frontiers in Pharmacology·Taiyi WangYu-Ling Ma
Jun 2, 2018·BioMed Research International·Mengmeng ZhengChunchao Han
May 17, 2018·Frontiers in Pharmacology·Litao BaiJunping Wei
Jul 5, 2017·International Journal of Molecular Sciences·Shih-Hsiang LoZhih-Cherng Chen
May 10, 2019·Frontiers in Neuroscience·Lei LiuSylvain Doré
Aug 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xing HuangBing Wang
Dec 10, 2020·Journal of Intensive Care·Woo Hyun ChoHye Ju Yeo
Apr 10, 2021·The Journal of Pharmacy and Pharmacology·Jing XuHang Song
Aug 1, 2021·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Xin-Xin LingShan Gao
Nov 19, 2021·Chemical Biology & Drug Design·Li ZhouFan Yang

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