Roles of High-resolution Manometry in Predicting Incomplete Bolus Transit in Patients With Dysphagia

Journal of Clinical Gastroenterology
Zhaohong ShiJiande D Z Chen

Abstract

High-resolution manometry (HRM) is used to assess esophageal motility diseases. Abnormalities in a number of HRM parameters have been reported in patients with dysphagia. However, it is unclear whether some of abnormal HRM parameters are predictive of dysphagia. The aim of this retrospective study was to investigate the roles of HRM parameters in predicting incomplete bolus clearance (IBC) in patients with dysphagia using high-resolution impedance manometry. A total of 644 wet swallows were reviewed and analyzed in 63 patients with symptoms of dysphagia or reflux who underwent a clinical high-resolution impedance manometry test. IBC was defined based on impedance measurement. The relationship of each of abnormal HRM parameters with IBC was analyzed and their roles in predicting IBC were determined. Patients with symptoms of both dysphagia and reflux showed the highest IBC rate, and patients with symptoms of reflux had the lowest IBC rate. The IBC was more prevalent in the distal esophagus. Premature contractions and peristalsis with large breaks were associated with a higher IBC rate in the proximal esophagus (P<0.05); large breaks, ineffective peristalsis, and abnormalities of the esophageal gastric junction functions were ass...Continue Reading

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Citations

Jan 25, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Suyu HeHubertus Feussner
Feb 10, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Anam QureshiHenry P Parkman
Mar 28, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Benjamin D RogersC Prakash Gyawali

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