Roles of ubiquitination in pattern-recognition receptors and type I interferon receptor signaling

Cytokine
Annie Bibeau-Poirier, Marc J Servant

Abstract

Post-translational protein modifications are involved in all functions of living cells. This includes the ability of cells to recognize pathogens and regulate genes involved in their clearance, a concept known as innate immunity. While phosphorylation mechanisms play essential roles in regulating different aspects of the innate immune response, ubiquitination is now recognized as another post-translational modification that works in parallel with phosphorylation to orchestrate the final proper innate immune response against invading pathogens. More precisely, this review will discuss the most recent advances that address the role of ubiquitination in pattern-recognition receptors and type I interferon receptor signaling.

References

Jul 28, 1999·Protein Science : a Publication of the Protein Society·B A van der ReijdenJ H Jansen
Oct 19, 1999·Gene·Y MamaneJ Hiscott
Oct 5, 2001·Clinical Microbiology Reviews·C E Samuel
Oct 19, 2001·Oncogene·J R Bradley, J S Pober
Jun 22, 2002·Trends in Biochemical Sciences·Benjamin T KileDouglas J Hilton
Mar 23, 2004·Annual Review of Immunology·Yun-Cai Liu
Apr 27, 2004·Nature Immunology·Tsung-Hsien Chuang, Richard J Ulevitch
Jun 16, 2004·Current Opinion in Cell Biology·Lijun Sun, Zhijian J Chen
Sep 2, 2004·Nature Reviews. Molecular Cell Biology·Timothy Cardozo, Michele Pagano
Oct 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Kenya HondaTadatsugu Taniguchi
Nov 3, 2004·Nature Reviews. Molecular Cell Biology·Julie L Kadrmas, Mary C Beckerle
Jan 18, 2005·Trends in Biochemical Sciences·Karen Heyninck, Rudi Beyaert
Apr 20, 2005·Oncogene·Xiaolu L Ang, J Wade Harper
Jun 21, 2005·Immunity·Takashi TanakaMichael J Grusby
Aug 3, 2005·Nature Reviews. Molecular Cell Biology·Linda HickeChristopher P Hill
Sep 22, 2005·Nature Reviews. Microbiology·Sébastien NisoleAli Saïb
Sep 28, 2005·Nature Immunology·Shintaro SatoShizuo Akira
Dec 3, 2005·Nature Reviews. Immunology·Yun-Cai LiuMichael Karin
Dec 6, 2005·Cell·Sebastian M B NijmanRené Bernards
Apr 20, 2006·Trends in Molecular Medicine·Kasper Hoebe, Bruce Beutler
Apr 25, 2006·Nature Reviews. Cancer·Keiichi I Nakayama, Keiko Nakayama
Jul 25, 2006·Nature Immunology·Masahiro YamamotoShizuo Akira
Sep 14, 2006·The Journal of Biological Chemistry·Colleen FearnsTsung-Hsien Chuang
Oct 19, 2006·Science's STKE : Signal Transduction Knowledge Environment·Hans Häcker, Michael Karin
Oct 31, 2006·Biochemical and Biophysical Research Communications·Norie NakasatoSatoshi Inoue
Mar 1, 2007·The Journal of Biological Chemistry·Beichu Guo, Genhong Cheng
Mar 3, 2007·Annual Review of Biochemistry·Myeong Sup Lee, Young-Joon Kim
Apr 27, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kei-ichiro ArimotoKunitada Shimotohno
May 15, 2007·Oncogene·A AdhikariZ J Chen
May 26, 2007·Nature Reviews. Immunology·Akihiko YoshimuraMasato Kubo
May 29, 2007·The Journal of Biological Chemistry·Daniel PanneStephen C Harrison

❮ Previous
Next ❯

Citations

Jan 6, 2010·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Stefan WieczorekJörg T Epplen
Feb 26, 2010·Journal of Virology·Mark A ClementzSusan C Baker
Apr 22, 2009·Molecular and Cellular Biology·Suzanne PazJohn Hiscott
Aug 15, 2009·Journal of Innate Immunity·Ronald N HartyAtsushi Okumura
May 11, 2011·Immunotherapy·Courtney Nicholas, Gregory B Lesinski
Mar 8, 2012·Growth Factors·Serge Y Fuchs
Nov 28, 2015·Journal of Molecular Cell Biology·Yong RanYan-Yi Wang
Sep 30, 2009·Biochemical and Biophysical Research Communications·Yuanyuan RuanJianxin Gu
Jun 16, 2009·Cellular Microbiology·Thomas SpallekVera Göhre
Aug 16, 2015·Biophysical Journal·Emine Guven-MaiorovRuth Nussinov
May 22, 2016·Biochimica Et Biophysica Acta·Emine Guven-MaiorovRuth Nussinov
Jan 25, 2017·Journal of Immunology Research·Da-Wei YehTsung-Hsien Chuang
Jun 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xiguang QiLirong Wang
Feb 13, 2021·Journal of Clinical Medicine·Eleni ChouriMarzia Rossato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.