Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation

Neuron
Kristin L Eckel-Mahan, Daniel R Storm

Abstract

Long-term changes in synaptic plasticity require new protein synthesis. This preview discusses data from Kim et al. (this issues of Neuron) that demonstrate the requirement of a novel, nucleolar protein, LLP (LAPS18-like protein), for the formation of long-term facilitation in Aplysia. LLP binds to and transcriptionally activates C/EBP, thereby promoting the formation of long-term facilitation and behavioral sensitization.

Citations

Feb 22, 2012·Trends in Neurosciences·Cristina M Alberini, Dillon Y Chen
Dec 15, 2007·Biochemical and Biophysical Research Communications·Jingxian Liu, Jianxing Song

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Forebrain & Food Avoidance

Neurons in the basal forebrain play specific roles in regulating feeding. Here are the latest discoveries pertaining to the basal forebrain and food avoidance.

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.