Abstract
Rosacea is one of the most common chronic dermatological diseases. It is characterized by transient or persistent facial erythema, teleangiectasias, papules and pustules, usually on the central portion of the face. Rosacea can be classified into four main subtypes: erythemato-teleangiectatic, papulopustular, phymatous, and ocular. These subtypes require different therapeutic approaches. Regarding to the pathomechanism, several hypotheses have been documented in the literature, including genetic and environmental factors, vascular abnormalities, dermal matrix degeneration, microorganisms such as Demodex folliculorum and Helicobacter pylori, but the cause of rosacea is still not known. Authors in this article review current literature on new classification system of rosacea, as well as the main pathogenetic theories and current therapeutic options.
References
Oct 1, 1992·International Journal of Dermatology·B AmichaiS Halevy
Dec 1, 1991·Journal of the American Academy of Dermatology·K F HelmC H Dicken
Jan 1, 1981·The Journal of Investigative Dermatology·J K Wilkin
Mar 1, 1994·Archives of Dermatology·G A ErtlA M Kligman
Mar 1, 1994·Archives of Dermatology·J K Wilkin
Jan 1, 1994·Dermatology : International Journal for Clinical and Investigative Dermatology·T JansenA M Kligman
Mar 1, 1993·Journal of the American Academy of Dermatology·E BonnarF C Powell
Mar 1, 1997·Journal of the Royal Society of Medicine·T Jansen, G Plewig
Dec 31, 1997·Ophthalmology·E K AkpekC S Foster
Nov 13, 2001·American Journal of Clinical Dermatology·K J McClellan, S Noble
Jan 5, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·S GeorgalaK Aroni
Mar 22, 2002·Journal of the American Academy of Dermatology·Jonathan WilkinFrank Powell
Sep 13, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·A Szlachcic
Oct 26, 2002·Dermatology : International Journal for Clinical and Investigative Dermatology·Mukadder KoçakMeral Ekşioğlu
Apr 21, 2004·Archives of Dermatology·Adolfo Fernandez-Obregon
May 22, 2004·Journal of the American Academy of Dermatology·Jonathan WilkinUNKNOWN National Rosacea Society Expert Committee
Sep 1, 2004·Journal of the American Academy of Dermatology·Glen H CrawfordWilliam D James
Oct 2, 2004·Dermatology : International Journal for Clinical and Investigative Dermatology·Kyriaki AroniEmmanouil Agapitos
Feb 23, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Stanislaw A Buechner
Jul 29, 2005·Facial Plastic Surgery : FPS·Kristina Zakhary, David A F Ellis
Sep 16, 2005·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M GatzkaM Lüftl
Sep 21, 2005·Archives of Dermatology·Christopher R Gorman, Stephen W White
Feb 21, 2006·Journal of the American Academy of Dermatology·Fouad El SayedJacques Bazex
May 20, 2006·Acta Dermato-venereologica·Vincenzo BettoliAnnarosa Virgili
Jul 29, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·N MeykadehM Fischer
Sep 12, 2006·International Journal of Dermatology·Emmanuel ClytiP Couppie