PMID: 1213142Jul 1, 1975Paper

Rosanol: electrophysiologic and biophysical study

Farmakologiia i toksikologiia
G NeshevT Tomov

Abstract

It has been established that rosanol, obtained from bulgarian rose oil, averts fatal disturbances of the cardiac rhythm induced by calcium dichloride and also prevents the onset of severe changes on the electrocardiogram provoked by a high-frequency electric stimulation of the mesencephalic reticular formation and by an intravenous administration of high doses of norepinepharine. In experiments on mitochondria the authors make an attempt to explain this antiarhythmic effect of rosanol by stabilization of the membranous potential.

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