Rotating sample system: an equivalent of a rotating electrode for microliter samples

Analytical Chemistry
A Cserey, M Gratzl

Abstract

Voltammetric experiments in sample droplets of 20 microL volume were carried out with gold ring electrodes microfabricated on Pyrex substrates. The droplet studied was centered and kept in place by a hydrophobic ring deposited on the substrate around the ring electrode, which also ensured that each sample assume a semispherical shape. A small hole in the center of the substrate filled with an agar gel membrane served as a junction. A mild jet of humidified nitrogen gas directed tangentially at the droplet caused it to rotate at a high rate. Cyclic voltammetry and constant-potential electrolysis of potassium ferricyanide were used to characterize this rotating sample system and to calculate diffusion layer thickness. The results clearly demonstrate that rotating of a semispherical microsample placed above a stationary ring electrode with a mild gas jet can be as effective as a rotating electrode system. As a practical example, voltammetric stripping analysis of 20-120 pmol mercuric nitrate samples was performed with a calibration of good linearity (r2 = 0.988) and a time constant for exhaustive electrolysis of approximately 2 min.

References

Nov 1, 1996·Analytical Chemistry·T Ishiyama, T Tanaka

❮ Previous
Next ❯

Citations

Sep 30, 2008·Analytical and Bioanalytical Chemistry·Linus T KaoMiklós Gratzl
Nov 8, 2005·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Gautam N ShettyMiklós Gratzl
Mar 31, 2009·Analytical Biochemistry·Linus T-H Kao, Miklós Gratzl
Jul 6, 2017·Analytical Chemistry·Magdalena KundysWojciech Adamiak
Apr 30, 2008·Analytical Chemistry·Linus T-H KaoMiklós Gratzl
Feb 17, 2009·Analytical Chemistry·Disha B ShethMiklós Gratzl

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry
Gautam N ShettyM Gratzl
Analytical and Bioanalytical Chemistry
Peter Gründler, Andreas Beckmann
© 2022 Meta ULC. All rights reserved