Rotavirus stability and inactivation

The Journal of General Virology
M K EstesCharles P Gerba

Abstract

The stability of the infectivity of Simian rotavirus, SA11, has been analysed and compared to the stability of reovirus type 1. SA11 infectivity was stable to freeze-thawing, sonication, incubation at 25 degrees C overnight or at 37 degrees C for 1 h and to treatment with acid, ether, chloroform and Genetron. In contrast to reovirus, the infectivity of SA11 was more rapidly inactivated by heating at 50 degrees C. SA11 infectivity was inactivated above pH 10.0 and by heating at 50 degrees C in 2 M-MgCl2, but was stabilized by heating in 2 m-MgSO4; reovirus 1 infectivity was enhanced by heating in MgCl2. Both SA11 and reovirus 1 were inactivated by freezing in MgCl2. These results show that rotaviruses and reoviruses can be distinguished by their patterns of inactivation by physical and chemical agents.

References

Jan 1, 1984·Archives of Virology·H SuzukiN Ishida
Jan 1, 1981·Archives of Virology·J A ShirleyT H Flewett
Jan 1, 1980·Archives of Virology·M K Estes, D Y Graham
Jan 1, 1987·Archives of Virology·D Y GrahamM K Estes
Jan 1, 1988·Archives of Virology·T N TanakaM K Estes
Aug 1, 1994·Comparative Immunology, Microbiology and Infectious Diseases·G Donelli, F Superti
Feb 1, 1982·Journal of Virological Methods·G BittonS R Farrah
Nov 15, 2000·International Journal of Food Microbiology·J O'MahonyC Hill
Jun 26, 2010·Foodborne Pathogens and Disease·Xiaowei SuDoris H D'Souza
Aug 5, 2010·Critical Care Medicine·Linda D Bobo, Erik R Dubberke
Jan 17, 2012·Applied and Environmental Microbiology·Ryan G SinclairCharles N Haas
Jul 9, 2004·Applied and Environmental Microbiology·Santiago CaballeroAlbert Bosch
Jul 3, 2013·Annual Review of Microbiology·Brian R Wasik, Paul E Turner
Jun 1, 1992·The Journal of Clinical Investigation·D M BassH B Greenberg
May 20, 2008·Water Research·Katrina J CharlesNicholas J Ashbolt
Mar 24, 2009·Journal of Applied Microbiology·S A RutjesA M de Roda Husman
Aug 18, 2004·Research in Microbiology·Fabienne LoisyFrançoise S Le Guyader
Mar 24, 2012·The Journal of General Virology·G De LorenzoF Arnoldi
Oct 15, 2014·Evolution; International Journal of Organic Evolution·Brian R WasikPaul E Turner
Mar 31, 2015·The Science of the Total Environment·Maria Elisa MagriBjörn Vinnerås
Jul 13, 2014·Virus Research·Ulrich Desselberger
Dec 21, 2014·Food and Environmental Virology·Sabastine E Arthur, Kristen E Gibson
Jan 1, 1997·Memórias do Instituto Oswaldo Cruz·D U MehnertJ A Candeias
Nov 2, 2018·Journal of Virology·Anthony J SnyderPranav Danthi
Jan 1, 1983·Journal of Cellular Biochemistry·B L EricsonM K Estes
Sep 18, 2002·Journal of Food Protection·M A Khadre, A E Yousef
Apr 9, 2020·European Journal of Medical Research·D PförringerA Obermeier
Jun 5, 2008·Journal of Food Protection·Yap Kok LeongOng Kien Chia

Related Concepts

RNA Viruses
Virus Replication
Kidney
Mycoreovirus
Solvents
Anthropoidea
Metal Antagonists
Neonatal Calf Diarrhea Virus
Hydrogen-Ion Concentration
Trypure

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.