Routine changing of intravenous administration sets does not reduce colonization or infection in central venous catheters

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Claire M RickardPeter Daley

Abstract

To determine the effect of routine intravenous (IV) administration set changes on central venous catheter (CVC) colonization and catheter-related bacteremia. Prospective, randomized, controlled trial. Eighteen-bed intensive care unit (ICU) in a large metropolitan hospital. Two hundred fifty-one patients with 404 chlorhexidine gluconate and silver sulfadiazine-coated multi-lumen CVCs. CVCs inserted in the ICU and in situ on day 4 were randomized to have their IV administration sets changed on day 4 (n = 203) or not at all (n = 201). Use of fluid containers and blood product administration sets was limited to 24 hours. CVCs were removed when not required, infection was suspected, or in place on day 7. Catheter cultures were performed on removal by blinded laboratory staff. Catheter-related bacteremia was diagnosed by a blinded intensivist using strict definitions. Data were collected regarding catheter duration, site, Acute Physiology and Chronic Health Evaluation (APACHE) II score, patient age, diagnosis, hyperglycemia, hypoalbuminemia, immune status, number of fluid containers and IV injections, and administration of propofol, blood, total parenteral nutrition, or lipid infusion. There were 10 colonized CVCs in the group receiv...Continue Reading

References

Aug 1, 1979·Annals of Internal Medicine·J D Band, D G Maki
Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
May 1, 1979·Annals of Internal Medicine·A E BuxtonJ E McGowan
Nov 1, 1986·The Journal of Hospital Infection·C J JakobsenJ I Madsen
Mar 1, 1987·Infection Control : IC·D R SnydmanW J Martin
May 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·A Sitges-SerraL Lorente
Dec 1, 1973·Annals of Internal Medicine·D G MakiF S Rhame
Apr 27, 1984·JAMA : the Journal of the American Medical Association·H F GorbeaW J Martin
Mar 1, 1995·Journal of Advanced Nursing·A J Walters
Dec 21, 1994·JAMA : the Journal of the American Medical Association·D Heiselman
Sep 1, 1994·Critical Care Medicine·M K O'MalleyR C McComb
Mar 1, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T S ElliottM H Faroqui
Jan 26, 1999·JAMA : the Journal of the American Medical Association·D L VeenstraS D Sullivan
Apr 15, 1999·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·M FoxS Muttitt
Aug 4, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·A G MatlowE L Ford-Jones
Nov 30, 2000·Anaesthesia and Intensive Care·D J FraenkelJ Lipman
Apr 20, 2001·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·I RaadG Mansour
Jan 31, 2002·Intensive Care Medicine·K H Polderman, A R J Girbes

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Citations

Apr 21, 2005·Der Internist·A F Widmer
Mar 18, 2009·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Jeannette Meyer
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC)
Apr 29, 2011·American Journal of Infection Control·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Oct 18, 2008·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Claire M Rickard
Oct 14, 2009·Journal of Clinical Nursing·Claire M RickardGillian Ray-Barruel
Nov 28, 2009·Journal of Nursing Management·Amanda HendersonKerri Holzhauser
Sep 21, 2006·The Journal of Hospital Infection·P Gastmeier, C Geffers
Apr 5, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ming-Horng TsaiYhu-Chering Huang
Sep 15, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Mary-Louise McLaws, Geoffrey Berry
Jul 7, 2017·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Nancy HedlundIdal Beer
Jul 14, 2016·The Cochrane Database of Systematic Reviews·Nai Ming LaiKenneth Tan
Jul 19, 2011·Journal of Intensive Care Medicine·Kevin R KastenRichard J Kagan
Jul 29, 2016·British Journal of Nursing : BJN·Claire Rickard
Sep 17, 2013·The Cochrane Database of Systematic Reviews·Amanda J UllmanClaire M Rickard
Aug 24, 2017·Journal of Veterinary Emergency and Critical Care·Julien GuillauminJoshua B Daniels

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