Routine screening of donor hearts by coronary angiography is feasible

Transplantation Proceedings
Onnen GrauhanRoland Hetzer

Abstract

Because of the shortage of donor hearts, the criteria for acceptance have been considerably extended. Meanwhile every fourth heart donor in Europe is over 50 years old. As we have previously demonstrated, transmission of preexisting coronary atherosclerosis (CAS) by means of transplantation is not rare. Transmitted CAS results in a 2- to 3-fold increased risk for early graft failure after heart transplantation (HTX). Nevertheless, in most cases donor angiograms are not considered feasible. In May 2003 in the northeast region of the Deutsche Stiftung Organtransplantation (DSO-NO), we introduced the guideline that every donor over 40 years old must be screened by angiography. Up to May 2003, fewer than 5% of donors had been screened by angiography; this situation is the rule in most Eurotransplant regions at present. Since May 2003 in the DSO-NO region, 85% of all donors over 40 years old were screened by angiography. Seventy percent of all donor hospitals--offering 90% of all donors--had an angiography facility. The additional costs of approximately euro 800 per donor angiogram were compensated by fewer fruitless airplane missions when CAS was diagnosed by the surgeon on the spot, which cost on average about euro 5,000 each. In ...Continue Reading

References

Aug 1, 1993·Journal of the American College of Cardiology·A JosephJ Kupersmith
Sep 24, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Onnen Grauhan, Roland Hetzer

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Citations

Jul 16, 2010·Wiener klinische Wochenschrift·Daniel HöferUNKNOWN Arbeitskreis "Herztransplantation" der Österreichischen Gesellschaft für Kardiologie
Mar 29, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tonino BombardiniEugenio Picano
Apr 5, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Razi AbuanzehRajamiyer V Venkateswaran
Dec 30, 2014·Circulation·Chris AnthonyPeter Macdonald
May 16, 2015·Critical Care Medicine·Robert M KotloffUNKNOWN Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Donor
Sep 17, 2020·Circulation. Heart Failure·Elizabeth D KrebsLeora T Yarboro
Jun 28, 2012·International Anesthesiology Clinics·Kathirvel Subramaniam
Aug 10, 2018·International Journal of Cardiology·Fabrice IvanesRichard Dorent

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